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Three hundred eight subjects (65 \u00b1 8 years, 44% female) were selected from the Subjective Cognitive Impairment Cohort (SCIENCe) project. All subjects answered two sleep questionnaires, Berlin Questionnaire (sleep apnea) and Pittsburgh Sleep Quality Index (sleep quality) and underwent a standardized memory clinic work\u2010up. One hundred ninety\u2010eight (64%) subjects reported sleep problems, based on 107 (35%) positive screenings on sleep apnea and 162 (53%) on poor sleep quality. Subjects with sleep problems reported more severe depressive symptoms, more anxiety, and more severe SCD. Cognitive tests, MRI, and CSF biomarkers did not differ between groups. Our results suggest that improvement of sleep quality and behaviors are potential leads for treatment in many subjects with SCD to relieve the experienced cognitive complaints.<\/jats:p>","DOI":"10.1002\/dad2.12287","type":"journal-article","created":{"date-parts":[[2022,5,15]],"date-time":"2022-05-15T07:48:30Z","timestamp":1652600910000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Subjective cognitive decline and self\u2010reported sleep problems: The SCIENCe project"],"prefix":"10.1002","volume":"14","author":[{"given":"Lieza G.","family":"Exalto","sequence":"first","affiliation":[{"name":"Department of Neurology, UMCU Brain Centre University Medical Center Utrecht  Utrecht the Netherlands"},{"name":"Alzheimer's Center Amsterdam, Department of Neurology Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC  Amsterdam the 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