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Group\u2010based multi\u2010trajectory modeling identified joint cognitive trajectories. Multinomial logistic regression examined the association of grip strength and gait speed at baseline with cognitive trajectories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>High performers (14.3%, <jats:italic>n<\/jats:italic>\u00a0=\u00a02298) and low performers (4.0%, <jats:italic>n<\/jats:italic>\u00a0=\u00a0642) were compared to the average performers (21.8%, <jats:italic>n<\/jats:italic>\u00a0=\u00a03492). Grip strength and gait speed were positively associated with high performance and negatively with low performance (<jats:italic>P<\/jats:italic>\u2010values\u00a0&lt;\u00a00.01). The association between grip strength and high performance was stronger in women (interaction <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), while gait speed was a stronger predictor of low performance in men (interaction <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Grip strength and gait speed are associated with cognitive trajectories in older age, but with sex differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>There is inter\u2010individual variability in late\u2010life cognitive trajectories.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Grip strength and gait speed predicted cognitive trajectories in older age.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>However, sex\u2010specific associations were identified.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In women, grip strength strongly predicted high, compared to average, trajectory.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In men, gait speed was a stronger predictor of low cognitive performance trajectory.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/dad2.12388","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T12:05:20Z","timestamp":1676376320000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Grip strength, gait speed, and trajectories of cognitive function in community\u2010dwelling older adults: A prospective study"],"prefix":"10.1002","volume":"15","author":[{"given":"Zimu","family":"Wu","sequence":"first","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn 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