{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:20:54Z","timestamp":1791580854065,"version":"4.3.4"},"reference-count":57,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":38,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp; Dem Diag Ass &amp; Dis Mo"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Remote smartphone assessments of cognition, speech\/language, and motor functioning in frontotemporal dementia (FTD) could enable decentralized clinical trials and improve access to research. We studied the feasibility and acceptability of remote smartphone data collection in FTD research using the ALLFTD Mobile App (ALLFTD\u2010mApp).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A diagnostically mixed sample of 214 participants with FTD or from familial FTD kindreds (asymptomatic: CDR\u00ae+NACC\u2010FTLD\u00a0=\u00a00 [<jats:italic>N<\/jats:italic>\u00a0=\u00a0101]; prodromal: 0.5 [<jats:italic>N<\/jats:italic>\u00a0=\u00a049]; symptomatic \u22651 [<jats:italic>N<\/jats:italic>\u00a0=\u00a051]; not measured [<jats:italic>N<\/jats:italic>\u00a0=\u00a013]) were asked to complete ALLFTD\u2010mApp tests on their smartphone three times within 12 days. They completed smartphone familiarity and participation experience surveys.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>It was feasible for participants to complete the ALLFTD\u2010mApp on their own smartphones. Participants reported high smartphone familiarity, completed \u223c 70% of tasks, and considered the time commitment acceptable (98% of respondents). Greater disease severity was associated with poorer performance across several tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These findings suggest that the ALLFTD\u2010mApp study protocol is feasible and acceptable for remote FTD research.<\/jats:p><\/jats:sec><jats:sec><jats:title>HIGHLIGHTS<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>The ALLFTD Mobile App is a smartphone\u2010based platform for remote, self\u2010administered data collection.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The ALLFTD Mobile App consists of a comprehensive battery of surveys and tests of executive functioning, memory, speech and language, and motor abilities.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Remote digital data collection using the ALLFTD Mobile App was feasible in a multicenter research consortium that studies FTD. Data was collected in healthy controls and participants with a range of diagnoses, particularly FTD spectrum disorders.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Remote digital data collection was well accepted by participants with a variety of diagnoses.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/dad2.12423","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T21:04:33Z","timestamp":1683752673000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6431-9956","authenticated-orcid":false,"given":"Jack Carson","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Neurology, Memory and Aging Center, University of California, San 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