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DNA genotyping was performed per manufacturers\u2019 protocols.<\/jats:p><jats:p><jats:bold>RESULTS<\/jats:bold>: Allele and genotype frequencies for 9 of the 11 single nucleotide polymorphisms (two apolipoprotein E variants<jats:italic>, CR1, BIN1, DRB1, NYAP1, PTK2B, FERMT2<\/jats:italic>, and <jats:italic>ABCA7<\/jats:italic>) differed significantly between MAs and NHWs.<\/jats:p><jats:p><jats:bold>DISCUSSION<\/jats:bold>: The significant differences in frequencies of top AD risk alleles observed here across MAs and NHWs suggest that ethnicity\u2010specific genetic risks for AD exist. Given our results, we are advancing additional projects to further elucidate ethnicity\u2010specific differences in AD.<\/jats:p>","DOI":"10.1002\/dad2.12518","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T20:14:06Z","timestamp":1703708046000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Top Alzheimer's disease risk allele frequencies differ in HABS\u2010HD Mexican\u2010 versus Non\u2010Hispanic White Americans"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3597-481X","authenticated-orcid":false,"given":"Mohammad","family":"Housini","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Neuroscience School of Biomedical Sciences University of North Texas Health Science Center  Fort Worth Texas USA"},{"name":"Department of Family Medicine &amp; Manipulative Medicine Texas College of Osteopathic Medicine University 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