{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:34:32Z","timestamp":1790048072727,"version":"4.0.1"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"vor","delay-in-days":52,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["10510032120003"],"award-info":[{"award-number":["10510032120003"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp;amp; Dem Diag Ass &amp;amp; Dis Mo"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Recent advancements in Alzheimer's disease (AD) biomarker research and clinical trials prompt reflection on the value and consequently appropriate use of tau positron emission tomography (tau\u2010PET) in the future.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>We conducted an online survey among dementia and PET experts worldwide to investigate the anticipated future role of tau\u2010PET in clinical practice and trials.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Two hundred sixty\u2010eight dementia experts, comprising 143 clinicians and 121 researchers, covering six continents participated. The vast majority (90%) fostered a positive attitude toward the added value of tau\u2010PET in clinical practice, particularly for staging, diagnosing, monitoring, and prognostication in a cognitively impaired memory clinic population. Experts anticipated an important role for tau\u2010PET for participant selection (76%\u2013100%) and measuring endpoints (75%\u201397%), in both anti\u2010amyloid and anti\u2010tau drug trials.<\/jats:p><\/jats:sec><jats:sec><jats:title>DISCUSSION<\/jats:title><jats:p>Our global survey study shows that dementia experts envision an important role for tau\u2010PET in the future, both in clinical practice and in drug trials, beyond current guidelines and practices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Dementia experts envision an important role for tau\u2010PET in the future.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Experts indicate that a tau\u2010PET scan could influence patient management.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Experts anticipate the utility of tau\u2010PET for participant selection and endpoints in drug trials.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>There is a gap between the anticipated usefulness of tau\u2010PET and current clinical practices.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/dad2.70033","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T05:46:11Z","timestamp":1732254371000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Survey among experts on the future role of tau\u2010PET in clinical practice and trials"],"prefix":"10.1002","volume":"16","author":[{"given":"Marie R.","family":"Vermeiren","sequence":"first","affiliation":[{"name":"Alzheimer Center Amsterdam, Neurology Vrije Universiteit Amsterdam Amsterdam UMC  Amsterdam The Netherlands"},{"name":"Radiology &amp; 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