{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:54:16Z","timestamp":1782881656860,"version":"3.54.5"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":76,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013263","name":"Nasjonalforeningen for Folkehelsen","doi-asserted-by":"publisher","award":["73299"],"award-info":[{"award-number":["73299"]}],"id":[{"id":"10.13039\/501100013263","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp;amp; Dem Diag Ass &amp;amp; Dis Mo"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>INTRODUCTION<\/jats:title><jats:p>It is unclear how dementia affects loss in life expectancy (LE). In this registry\u2010based study, we aimed to study sex differences in LE and loss in LE in dementia, mild cognitive impairment (MCI), and subjective cognitive decline (SCD).<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>A total of 16,358 patients diagnosed with dementia, MCI, or SCD from the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) during 2009\u20132022 were included and followed up for mortality. Sex differences in LE and loss in LE were predicted using flexible parametric survival models and sex\u2010specific mortality in the general population as reference.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Among dementia patients, women with dementia had the largest loss in LE: 17 years loss at 60 years; correspondingly, men lost 13.5 years. Similar patterns were observed for MCI and dementia subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>DISCUSSION<\/jats:title><jats:p>Women with dementia or MCI had a larger loss in LE compared to men with these diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Highlights<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Women with dementia had the largest loss in life expectancy compared to the general population.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The excess female loss in life expectancy was also evident for all the dementia subtypes and for mild cognitive impairment.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The loss in life expectancy was more pronounced in younger patients with dementia, with a loss of 17 years in women at 60 years of age. Men, in comparison, lost 13.5 years at the same age.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Subjective cognitive decline was associated with a minor loss in life expectancy in both sexes.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/dad2.70177","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T11:40:03Z","timestamp":1757936403000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sex differences in life expectancy in dementia, mild cognitive impairment (MCI), and subjective cognitive decline (SCD)"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8807-5671","authenticated-orcid":false,"given":"Rachel","family":"Amland","sequence":"first","affiliation":[{"name":"The Norwegian National Centre for Ageing and Health Vestfold Hospital Trust  T\u00f8nsberg Norway"},{"name":"Department of Geriatric Medicine Oslo University Hospital  Oslo Norway"},{"name":"Faculty of Medicine Institute of Health and Society University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geir","family":"Selb\u00e6k","sequence":"additional","affiliation":[{"name":"The Norwegian National Centre for Ageing and Health Vestfold Hospital Trust  T\u00f8nsberg Norway"},{"name":"Department of Geriatric Medicine Oslo University Hospital  Oslo Norway"},{"name":"Faculty of Medicine Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Br\u00e6khus","sequence":"additional","affiliation":[{"name":"The Norwegian National Centre for Ageing and Health Vestfold Hospital Trust  T\u00f8nsberg Norway"},{"name":"Department of Geriatric Medicine Oslo University Hospital  Oslo Norway"},{"name":"Department of Neurology Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanneke F. 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