{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:50:59Z","timestamp":1791395459290,"version":"4.3.3"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009886","name":"Regione Puglia","doi-asserted-by":"publisher","award":["1424\/2025"],"award-info":[{"award-number":["1424\/2025"]}],"id":[{"id":"10.13039\/501100009886","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp;amp; Dem Diag Ass &amp;amp; Dis Mo"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>We aimed to assess dementia care organizations within a southern Italian local health authority (Azienda Sanitaria Locale di Barletta Andria Trani) and to propose an equitable implementation framework for anti\u2010amyloid therapies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We performed a retrospective analysis of dementia\u2010related outpatient activity in 2024 patients across 18 district clinics (primary care clinics) and three specialized centers for cognitive disorders and dementia (specialized memory centers), integrating booking, clinical, imaging, and prescribing data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Among 1158 initial evaluations, specialized memory centers showed substantially higher quality indicators than district clinics: Mini\u2010Mental State Examination documentation (80.0% vs. 6.6%,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), full clinical documentation (95.5% vs. 10.0%), higher use of magnetic resonance imaging and amyloid positron emission tomography, and 5\u2010fold higher rate of prescribing acetylcholinesterase inhibitors. Validated radiological scoring and biomarker facilities (cerebrospinal fluid, apolipoprotein E genotyping) were largely unavailable.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>Major organizational gaps limit readiness for disease\u2010modifying Alzheimer's disease therapies. A four\u2010tier hub\u2010and\u2010spoke model may improve equity, efficiency, and safe implementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dad2.70403","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T02:56:49Z","timestamp":1783997809000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preparedness and quality of dementia care in an Italian health authority when introducing anti\u2010A\u03b2 therapies"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6069-7063","authenticated-orcid":false,"given":"Maurizio","family":"Giorelli","sequence":"first","affiliation":[{"name":"Operative Unit of Neurology \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Ada Di","family":"Paola","sequence":"additional","affiliation":[{"name":"Operative Unit of Neurology \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosangela","family":"Vallarelli","sequence":"additional","affiliation":[{"name":"Operative Unit of Neurology \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Negri","sequence":"additional","affiliation":[{"name":"Operative Unit of Neurology \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalba","family":"Morgese","sequence":"additional","affiliation":[{"name":"Primary Care Physician  Andria Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario Francesco","family":"Balzano","sequence":"additional","affiliation":[{"name":"Operative Unit of Radiology \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale Di","family":"Fazio","sequence":"additional","affiliation":[{"name":"Operative Unit of Nuclear Medicine \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Tat\u00f2","sequence":"additional","affiliation":[{"name":"Operative Unit of Clinic Pathology \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cataldo","family":"Procacci","sequence":"additional","affiliation":[{"name":"Pharmaceutical Department  Trani Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Masi","sequence":"additional","affiliation":[{"name":"Operative Unit of Neurology \u201cBonomo\u201d General Hospital  Andria Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica Lucia","family":"Carpagnano","sequence":"additional","affiliation":[{"name":"Healthcare Management \u201cDimiccoli\u201d General Hospital  Barletta Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Dimatteo","sequence":"additional","affiliation":[{"name":"General Director  Andria Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.937486"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2023.26"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265\u2010023\u201001858\u20109"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.005"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010190426"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40120\u2010022\u201000335\u2010x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00472"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cts.12491"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212948"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.13239"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1399121"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u20102009\u20101177"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A8469"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2022.21"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2023.46"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14031006"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072\u2010025\u201008576\u2010y"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072\u2010025\u201008143\u20105"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/13872877251331243"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.10.967"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.008"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm\u20102023\u20101434"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010024\u201011019\u20107"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000001177"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000200291"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2025.0065"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072\u2010025\u201007464\u20108"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2007.08.006"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2016.09.009"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010240594"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/13558196231211141"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.14283\/jpad.2023.94"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010240728"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2023.270"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.6157"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40120\u2010023\u201000504\u20106"}],"container-title":["Alzheimer's &amp; Dementia: Diagnosis, Assessment &amp; Disease Monitoring"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dad2.70403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dad2.70403","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dad2.70403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:56:50Z","timestamp":1791392210000},"score":1,"resource":{"primary":{"URL":"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/10.1002\/dad2.70403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/dad2.70403"],"URL":"https:\/\/doi.org\/10.1002\/dad2.70403","archive":["Portico"],"relation":{},"ISSN":["2352-8729","2352-8729"],"issn-type":[{"value":"2352-8729","type":"print"},{"value":"2352-8729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70403"}}