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PET scans were assessed by six nuclear medicine physicians against Centiloid (CL) quantification. An optimized reference region was utilized for FBP as it improved CL\u2013visual read correlations. Inter\u2010reader agreement of visual assessment was measured using Fleiss\u2019 Kappa.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Mean peak accuracy for visual read exceeded 95% for both NAV and FBP. However, peak accuracy for NAV visual reads was achieved at 14\u201315CL compared to 38\u201346CL for FBP. Higher inter\u2010reader agreement was observed for NAV compared to FBP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>For mild to moderate elevation in A\u03b2, visual read of NAV is more sensitive and consistent than visual read of FBP by both experienced and novice readers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dad2.70426","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:41:27Z","timestamp":1784259687000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Visual read performance of\n                    <sup>18<\/sup>\n                    F\u2010Florbetapir and\n                    <sup>18<\/sup>\n                    F\u2010NAV4694 A\u03b2 PET compared against Centiloid reference standard in a paired cohort"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6509-9687","authenticated-orcid":false,"given":"Ishara","family":"Paranawithana","sequence":"first","affiliation":[{"name":"The Australian e\u2010Health Research Centre Commonwealth Scientific and Industrial Research Organization  Melbourne Victoria Australia"},{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Dor\u00e9","sequence":"additional","affiliation":[{"name":"The Australian e\u2010Health Research Centre Commonwealth Scientific and Industrial Research Organization  Melbourne Victoria Australia"},{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierrick","family":"Bourgeat","sequence":"additional","affiliation":[{"name":"The Australian e\u2010Health Research Centre Commonwealth Scientific and Industrial Research Organization  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. B.","family":"Toh","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine The Royal Melbourne Hospital  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanyaluck","family":"Thientunyakit","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tawika","family":"Kaewchur","sequence":"additional","affiliation":[{"name":"PET\/CT and Cyclotron Center, Faculty of Medicine Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antony","family":"Sutherland","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley G.","family":"Gillman","sequence":"additional","affiliation":[{"name":"The Australian e\u2010Health Research Centre Commonwealth Scientific and Industrial Research Organization  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azadeh","family":"Feizpour","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"},{"name":"The Florey Institute of Neuroscience and Mental Health The University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurgen","family":"Fripp","sequence":"additional","affiliation":[{"name":"The Australian e\u2010Health Research Centre Commonwealth Scientific and Industrial Research Organization  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor L.","family":"Villemagne","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging &amp; Therapy Austin Health  Melbourne Victoria Australia"},{"name":"Department of Psychiatry University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher C.","family":"Rowe","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging &amp; 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