{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:51:05Z","timestamp":1791395465551,"version":"4.3.3"},"reference-count":65,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":36,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp;amp; Dem Diag Ass &amp;amp; Dis Mo"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>Dementia prevalence is rising with population aging, disproportionately affecting females and ethnically diverse groups. Physical activity (PA) may mitigate age\u2010related cognitive and brain decline; sex\u2010 and ethnicity\u2010specific associations remain poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Data from the Health and Aging Brain Study\u2010Health Disparities were analyzed from 3585 participants (63% female). PA was categorized using the Rapid Assessment of Physical Activity (RAPA) questionnaire as no\/little (&lt;\u00a04) or moderate\/high (\u2265\u00a04). Outcomes included cognitive composites, plasma biomarkers, and magnetic resonance imaging\u2013derived hippocampal subregions and dorsolateral prefrontal cortex volumes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Higher PA was associated with higher global cognition and executive functions in all females and in Hispanic males (\n                      <jats:italic>p<\/jats:italic>\n                      s\u00a0&lt;\u00a00.05), higher episodic memory and larger hippocampal volumes across participants (\n                      <jats:italic>p<\/jats:italic>\n                      s\u00a0&lt;\u00a00.05), and lower amyloid beta 40, total tau, and larger hippocampal subregion volumes in females (\n                      <jats:italic>p<\/jats:italic>\n                      s\u00a0&lt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Findings support PA as a modifiable factor associated with healthy brain aging, emphasizing the importance of incorporating sex and ethnicity into future research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dad2.70437","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T09:20:50Z","timestamp":1786008050000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Role of sex and ethnicity in the relationships among physical activity, cognition, and AD biomarkers in the HABS\u2010HD cohort"],"prefix":"10.1002","volume":"18","author":[{"given":"Jansie H.","family":"Nel","sequence":"first","affiliation":[{"name":"Barha Brain Health Laboratory, Faculty of Kinesiology University of Calgary  Calgary Alberta 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