{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:50:59Z","timestamp":1791395459662,"version":"4.3.3"},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":47,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Alz &amp;amp; Dem Diag Ass &amp;amp; Dis Mo"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>Behavioral variant frontotemporal dementia (bvFTD) is often misdiagnosed, particularly in psychiatric phenocopies of the disease (phFTD). We compared the top\u2010performing bvFTD\u2010specific behavioral tools, identified in a prior systematic review, for differentiating bvFTD from phFTD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>In this prospective diagnostic accuracy study, consecutively recruited participants with suspected bvFTD by a\u00a0specialist physician completed nine bvFTD\u2010specific tools at baseline with a blinded assessor. Final diagnoses were assigned by multidisciplinary consensus after follow\u2010up. Diagnostic performance was assessed using receiver operating characteristic analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Fifty\u2010one participants were included (25 bvFTD, 26 phFTD). The Frontotemporal Dementia versus Primary Psychiatric Disorder (FTDvsPPD) checklist showed the best discrimination (area under the curve [AUC] 0.92), with 80.0% sensitivity and 96.2% specificity. The Social Behavior Observer Checklist (SBOC) performed next best (AUC 0.85). The Informant Based Questionnaire and Pick's Disease Scale showed moderate discrimination and other tools performed poorly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>Tools focused on clinician observation outperformed informant\u2010reliant measures. The FTDvsPPD checklist showed the strongest rule\u2010in and rule\u2010out utility, while the SBOC provided useful rule\u2010in support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dad2.70452","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:44:20Z","timestamp":1787035460000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical tools to differentiate behavioral variant frontotemporal dementia from phenocopies"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2999-987X","authenticated-orcid":false,"given":"Joshua","family":"Flavell","sequence":"first","affiliation":[{"name":"Queensland Brain Institute The University of Queensland  Brisbane Queensland Australia"},{"name":"The Mater Memory and Cognitive Disorders Clinic The Mater Hospital  Brisbane Queensland Australia"},{"name":"Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soohyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Queensland Brain Institute The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin A. 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