{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:34:40Z","timestamp":1758630880150},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,2,27]],"date-time":"2002-02-27T00:00:00Z","timestamp":1014768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\u03b3\/\u03b4 T\u2010cell lymphoma is a rare neoplasm that is not well characterized and is associated with a poor prognosis. We report a case of \u03b3\/\u03b4 peripheral T\u2010cell lymphoma that appeared as a breast lump in a 35\u2010yr\u2010old woman. The patient was examined for a 2\u2010mo history of a right\u2010sided breast mass with associated hepatosplenomegaly 2 yr in duration. A fine\u2010needle aspiration biopsy (FNAB) was performed, and the diagnosis of lymphoma was rendered. The patient received two cycles of CHOP and is alive with persistent disease. FNAB showed evidence of polymorphous lymphoma, consisting of medium\u2010size to large cells with immature chromatin. Flow cytometric immunophenotyping showed expression of CD2, CD3, and CD7 with lack of expression of CD1a, CD4, CD5, CD8, and CD56. Flow cytometry also showed predominant expression of the \u03b3\/\u03b4 T\u2010cell receptor. Cytogenetic analysis showed 48XX+i7(q11.2),+7(3). Our case indicates that \u03b3\/\u03b4 peripheral T\u2010cell lymphoma can be diagnosed by FNAB. This rare entity requires further investigation. Diagn. Cytopathol. 2002;26:170\u2013173; DOI 10.1002\/dc.10072 \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.10072","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T23:09:26Z","timestamp":1030316966000},"page":"170-173","source":"Crossref","is-referenced-by-count":15,"title":["\u03b3\/\u03b4 Peripheral T\u2010cell lymphoma of the breast diagnosed by fine\u2010needle aspiration biopsy"],"prefix":"10.1002","volume":"26","author":[{"given":"S.","family":"Al Omran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.A.","family":"Mourad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,2,27]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8652(199901)60:1<61::AID-AJH10>3.0.CO;2-L"},{"issue":"3","key":"e_1_2_1_3_2","first-page":"186","article-title":"Gamma delta lymphoma: a clinicopathologic study of 6 cases including extrahepatosplenic type","volume":"69","author":"Yamaguchi M","year":"1999","journal-title":"Int J Hematol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199506000-00013"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880103"},{"issue":"11","key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"4265","DOI":"10.1182\/blood.V88.11.4265.bloodjournal88114265","article-title":"Hepatosplenic T\u2010cell lymphoma: a distinct clinicopathologic entity of cytotoxic \u03b3\/\u03b4 T\u2010cell origin","volume":"88","author":"Cooke CB","year":"1996","journal-title":"Blood"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2000.00772.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2400742"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2000.00804.x"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.10072","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.10072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T11:01:57Z","timestamp":1700391717000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.10072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,2,27]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,3]]}},"alternative-id":["10.1002\/dc.10072"],"URL":"https:\/\/doi.org\/10.1002\/dc.10072","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,2,27]]}}}