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Retrospective histopathological analysis of 70 LEEP products preceded by ASCUS was consistently detected by two consecutive Pap smears. The presence or absence of several histopathological findings in cases with (23\/70) and without (47\/70) histological diagnosis of SIL were compared. Immature squamous metaplasia, severe cervicitis, and tube\u2010endometrial metaplasia were found with similar frequency on positive and negative neoplastic disease specimens. Reactive squamous atypia, keratosis, atrophy, glandular reactive\/inflammatory atypia, tunnel clusters, and microglandular hyperplasia were less frequently found in LEEP specimens presenting with SIL. Reactive squamous atypia and keratosis were consistently associated with SIL absence and appear to be responsible for the cytological diagnosis of ASCUS (P &lt; 0.05). Diagn. Cytopathol. 2002;27:123\u2013127. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.10133","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T11:56:23Z","timestamp":1033905383000},"page":"123-127","source":"Crossref","is-referenced-by-count":3,"title":["Nonneoplastic findings in loop electrical excision procedure specimens from patients with persistent atypical squamous cells of uncertain significance in two consecutive pap smears"],"prefix":"10.1002","volume":"27","author":[{"given":"\u00c1lvaro P.","family":"Pinto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe F.B.","family":"Tuon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson L.A.","family":"Tizzot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Fernando","family":"Bleggi Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Martins","family":"Colla\u00e7o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,7,30]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"191","article-title":"Cyto\u2010histological correlation in 326 patients submitted to loop electrosurgical excision procedure in the Cervical Cancer Screening Program of the State of Paran\u00e1, Brazil","volume":"36","author":"Colla\u00e7o LM","year":"2000","journal-title":"J Bras Patol"},{"key":"e_1_2_1_3_2","first-page":"120","article-title":"Reproducibility of cytologic diagnosis: study of CRISAP Ile\u2010de\u2010France","volume":"28","author":"Barres D","year":"2000","journal-title":"Gynecol Obstet Fertil"},{"key":"e_1_2_1_4_2","volume-title":"Pathology of early cervical neoplasia in contemporary issues in surgical pathology","author":"Crum CR","year":"1997"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199910)21:4<292::AID-DC13>3.0.CO;2-N"},{"key":"e_1_2_1_6_2","first-page":"440","article-title":"Atypical squamous cells of undetermined significance. 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