{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T00:14:44Z","timestamp":1700352884568},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2002,11,25]],"date-time":"2002-11-25T00:00:00Z","timestamp":1038182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human papilloma virus (HPV) Hybrid Capture\u00ae II testing was introduced at our institution in mid\u2010April, 2001. Relatively little data exists on the histologic follow\u2010up of \u201chigh\u2010risk HPV\u2010positive ASCUS\u201d patients without a previous abnormal Pap result. The results of the cytologic\u2013histologic correlation of 50 patients over an 11\u2010mo period are presented. Our results indicate that significant lesions may be discovered in patients of the \u201chigh\u2010risk HPV\u2010positive ASCUS\u201d category who have no previous abnormal Pap history. Of the 50 patients presented in this study, histologic follow\u2010up demonstrated evidence of squamous carcinoma in one patient (2%), high\u2010grade squamous intraepithelial lesion (HSIL) in eight patients (16%), and low\u2010grade squamous intraepithelial lesion (LSIL) in 19 patients (38%). The other 22 (44%) showed chronic cervicitis, reactive changes, or no pathologic changes. These findings suggest a more aggressive clinical approach may be warranted in the management of new onset ASCUS positive for high risk HPV. Diagn. Cytopathol. 2002;27:382\u2013386. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.10198","type":"journal-article","created":{"date-parts":[[2002,11,26]],"date-time":"2002-11-26T17:40:01Z","timestamp":1038332401000},"page":"382-386","source":"Crossref","is-referenced-by-count":2,"title":["Role for HPV testing in ASCUS: A cytologic\u2010histologic correlation"],"prefix":"10.1002","volume":"27","author":[{"given":"Dwayne","family":"Crabtree","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"April","family":"Unkraut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Cozens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinda","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Pennington","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lois","family":"Chaney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blake","family":"Nestok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toni","family":"Robinson\u2010Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rawia","family":"Yassin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,11,25]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.4.293"},{"key":"e_1_2_1_3_2","first-page":"1","article-title":"Is there a role for HPV DNA testing in routine practice?","author":"Wright TC","year":"2001","journal-title":"OBG Manage"},{"key":"e_1_2_1_4_2","volume-title":"Thin Prep 2000 system operator's manual"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-0201-8"},{"key":"e_1_2_1_6_2","unstructured":"HPV DNA Test Hybrid Capture\u00ae II: package insert. Gaithersburg MD: Digene Corp."},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.17.1605"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2022"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2114"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6690523"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2120"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000333166"},{"key":"e_1_2_1_13_2","first-page":"56","article-title":"Experience with 40,000 Papanicolaou smears","volume":"48","author":"Sandmire HF","year":"1976","journal-title":"Am J Obstet Gynecol"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.10198","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.10198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T10:39:45Z","timestamp":1700303985000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.10198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11,25]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["10.1002\/dc.10198"],"URL":"https:\/\/doi.org\/10.1002\/dc.10198","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11,25]]}}}