{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T09:56:40Z","timestamp":1770890200721,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,1,30]],"date-time":"2003-01-30T00:00:00Z","timestamp":1043884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2003,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bench\u2010top fine\u2010needle aspiration biopsy (FNAB) following splenectomy and nephrectomy from a 21\u2010yr\u2010old female of tuberous sclerosis with right renal angiomyolipoma and splenic hamartoma was performed for the correlation of the cytologic features with histologic findings and, along with the immunopathologic studies, for the establishment of a challenging preoperative diagnosis of splenic hamartoma. The postoperative bench\u2010top aspirate of splenic hamartoma yielded small and large clusters of plump, spindly to polygonal cells in the blood\u2010stained background with scattered small lymphocytes, comparable with the preoperative echo\u2010guided FNAB. The histopathology and immunopatholgy of the splenic hamartoma from the bench\u2010top aspirate cytoblock and splenectomy tissue were comparable, unveiling the red pulp tissue consisting of wider cord stromal tissue than its normal counterpart with sinus\u2010like vascular channels lined by endothelial cells which were positive for CD8, CD34, factor VIII\u2010related antigen, vimentin, as well as negative for muscle\u2010specific actin, CD21, CD68, and cytokeratin, scattered dispersed CD3\u2010 and CD45RO\u2010positive T\u2010lymphocytes, and small clusters of CD20\u2010positive B lymphocytes, with a dearth of fibrous trabeculae and organized white\u2010pulp lymphoid tissue. A combination of cytologic features and immunopathologic results from the aspirate cytoblock along with the salient clinical information should enable an accurate preoperative diagnosis of splenic hamartoma. Diagn. Cytopathol. 2003;28:82\u201385. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.10230","type":"journal-article","created":{"date-parts":[[2003,1,31]],"date-time":"2003-01-31T14:46:44Z","timestamp":1044024404000},"page":"82-85","source":"Crossref","is-referenced-by-count":20,"title":["Fine\u2010needle aspiration cytology of splenic hamartoma"],"prefix":"10.1002","volume":"28","author":[{"given":"Sheng\u2010Huang","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,1,30]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"564","article-title":"Hamartoma of the spleen: a manifestation of tuberous sclerosis","volume":"41","author":"Darden JW","year":"1975","journal-title":"Am Surgeon"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1967.01330140155035"},{"key":"e_1_2_1_4_2","first-page":"391","article-title":"Splenic hamartoma. 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