{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T11:07:25Z","timestamp":1764587245236},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,2,27]],"date-time":"2003-02-27T00:00:00Z","timestamp":1046304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2003,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The diagnosis of malignant lymphomas by fine\u2010needle aspiration biopsy (FNAB) is increasing in utilization. The cytomorphologic distinction among the small B\u2010cell lymphomas may be quite difficult. We are unaware of anyone who has compared directly mantle cell lymphoma (MCL) and marginal zone lymphoma (MZL) in FNAB. Our major goal was to examine the cytomorphologic attributes of MCL and MZL and to look for features distinctive of or suggestive of either neoplasm. Seven immunophenotypic MCL and seven immunophenotypic MZL aspirates were evaluated for a number of cytomorphologic features in direct smears. Features favoring MCL include a relatively monomorphic cellular population, prominent nuclear membrane contour irregularities, and mitotic figures. Conversely, a polymorphic cellular population suggested MZL. However, due to extensive overlap of specific cytologic features, the two lymphomas cannot be definitively distinguished based solely on cytomorphology. Although there are cytomorphologic attributes suggestive of either MCL or MZL, considerable overlap exists. Based on an individual case basis, the distinction cannot be made reliably by morphology alone; ancillary studies, e.g., immunophenotyping, are essential. Diagn. Cytopathol. 2003;28:126\u2013130. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.10250","type":"journal-article","created":{"date-parts":[[2003,3,18]],"date-time":"2003-03-18T23:13:51Z","timestamp":1048029231000},"page":"126-130","source":"Crossref","is-referenced-by-count":21,"title":["Marginal zone and mantle cell lymphomas: Assessment of cytomorphology in subtyping small B\u2010cell lymphomas"],"prefix":"10.1002","volume":"28","author":[{"given":"Bettina A.","family":"Murphy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenton A.","family":"Meda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H.","family":"Buss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim R.","family":"Geisinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,2,27]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"209","article-title":"Immunocytochemical analysis and cytomorphologic diagnosis on fine needle aspirates of lymphoproliferative disease","volume":"32","author":"Tani EM","year":"1988","journal-title":"Acta Cytol"},{"key":"e_1_2_1_3_2","first-page":"311","article-title":"Morphologic and immunocytochemical evaluation of 220 fine needle aspirates of malignant lymphoma and lymphoid hyperplasia","volume":"34","author":"Sneige N","year":"1990","journal-title":"Acta Cytol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840080506"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199703)16:3<200::AID-DC2>3.0.CO;2-J"},{"key":"e_1_2_1_6_2","first-page":"37A","article-title":"Practical value of fine\u2010needle aspiration biopsy and flow cytometry in the diagnosis and classification of malignant lymphoma","volume":"11","author":"Dong HY","year":"1998","journal-title":"Mod Pathol"},{"key":"e_1_2_1_7_2","first-page":"46A","article-title":"Diagnostic role of flow cytometry in fine needle aspiration biopsy of lymph nodes performed for suspected lymphoma","volume":"12","author":"Kaleem Z","year":"1999","journal-title":"Mod Pathol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980825)84:4<252::AID-CNCR11>3.0.CO;2-R"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.51.3.189"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19991225)87:6<325::AID-CNCR3>3.0.CO;2-W"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910215)67:4<1003::AID-CNCR2820670424>3.0.CO;2-W"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1309\/0Q7F-QTGM-6DPD-TLGY"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1309\/MN6J-4NJY-C5CG-1PLH"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(200002)22:2<120::AID-DC14>3.0.CO;2-8"},{"key":"e_1_2_1_15_2","first-page":"853","article-title":"Diagnostic assessment of enlarged superficial lymph nodes by fine needle aspiration","volume":"37","author":"Pilotti S","year":"1993","journal-title":"Acta Cytol"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19990825)87:4<216::AID-CNCR9>3.0.CO;2-2"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19991225)87:6<322::AID-CNCR2>3.0.CO;2-1"},{"issue":"1","key":"e_1_2_1_18_2","first-page":"S8","article-title":"World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. 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