{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T17:46:03Z","timestamp":1700156763227},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,2,20]],"date-time":"2004-02-20T00:00:00Z","timestamp":1077235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Total joint replacement is a common orthopedic procedure. An artificial joint implant may fail due to mechanical mishap and a granulomatous reaction can be induced by the artificial joint debris after the mechanical failure. We report a case of an exaggerated pigmented granulomatous tissue response to metallic artificial joint implant debris in a 72\u2010yr\u2010old male that was mistaken for metastatic melanoma. The mass was soft, pigmented, ill\u2010defined, and located in the right inguinal region. Fine\u2010needle aspiration revealed numerous black\u2010pigment laden cells. The cellular features were frequently obscured by the heavy pigmentation. Occasional cells exhibited atypia and prominent nucleoli. There were also abundant extracellular irregular small black particles dispersed in the background. The diagnosis of melanoma involving a lymph node was made. Since there was no prior history of melanoma, it was presumed that this represented metastatic melanoma from an unknown primary. A subsequent exploration of the groin was performed with the intent to resect the disease. At exploration, the mass was found to be contiguous with the hip joint and the frozen section of the mass revealed no evidence of melanoma. The final tissue diagnosis confirmed the frozen section report and showed a granulomatous reaction. This report underscores the diagnostic dilemma associated with the exaggerated pigmented granulomatous reaction due to an artificial prosthesis. Diagn. Cytopathol. 2004;30:198\u2013200. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.20006","type":"journal-article","created":{"date-parts":[[2004,2,26]],"date-time":"2004-02-26T20:22:04Z","timestamp":1077826924000},"page":"198-200","source":"Crossref","is-referenced-by-count":5,"title":["Exaggerated pigmented granulomatous reaction to the artificial joint implant mimics metastatic melanoma"],"prefix":"10.1002","volume":"30","author":[{"given":"Wei","family":"Xin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robertson D.","family":"Davenport","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred E.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire W.","family":"Michael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,2,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"234","volume-title":"Diagnostic surgical pathology","author":"Bullough PG","year":"1999"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1309\/LWW3-5XK0-FKG9-HDRK"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1177\/106689699604030404","article-title":"Revision hip arthroplasty: a histologic review","volume":"3","author":"Shokeir MO","year":"1996","journal-title":"Int J Surg Pathol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199306000-00001"},{"key":"e_1_2_1_6_2","first-page":"140","article-title":"The pathology of failed large joint arthroplasty","volume":"261","author":"Mirra JM","year":"1990","journal-title":"Clin Orthop"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960815)78:4<834::AID-CNCR21>3.0.CO;2-V"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(79)90001-5"},{"key":"e_1_2_1_9_2","volume-title":"The arts & science of cytopathology: exfoliative cytology","author":"DeMay RM","year":"1996"},{"key":"e_1_2_1_10_2","first-page":"527","article-title":"Cytologic studies of malignant melanoma of the vagina","volume":"19","author":"Masubuchi S","year":"1975","journal-title":"Acta Cytol"},{"key":"e_1_2_1_11_2","first-page":"2237","volume-title":"Surgery\u2014scientific principles and practice","author":"Chang AE","year":"1997"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.20006","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.20006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T17:04:22Z","timestamp":1700154262000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.20006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2,20]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1002\/dc.20006"],"URL":"https:\/\/doi.org\/10.1002\/dc.20006","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2,20]]}}}