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Radiologically, it often results in a well\u2010defined osteolytic lesion\u2010mimicking tumor. A 68\u2010year\u2010old man who presented with chronic hip pain following total hip replacement was studied by fine\u2010needle aspiration. An ultrasound\u2010guided aspiration revealed hypercellular smears consisting predominantly of proliferating mesenchymal cells, foamy macrophages, inflammatory cells, and background acellular debris. Numerous multinucleated giant cells were observed as well. Differential diagnosis includes primary or metastatic clear\u2010cell tumors. Diagn. Cytopathol. 2004;31:259\u2013262. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.20102","type":"journal-article","created":{"date-parts":[[2004,9,27]],"date-time":"2004-09-27T16:01:17Z","timestamp":1096300877000},"page":"259-262","source":"Crossref","is-referenced-by-count":7,"title":["Particle disease: Cytopathologic findings of an unusual case"],"prefix":"10.1002","volume":"31","author":[{"given":"Anil V.","family":"Parwani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas P.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Z.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,27]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.5507\/bp.2002.004"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0883-5403(92)90050-Z"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520480070043"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002560050552"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002560050541"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200212000-00015"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.12.1047"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/145749690309200202"},{"issue":"1","key":"e_1_2_1_10_2","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.2106\/00004623-200300001-00002","article-title":"Cellular mechanisms of osteolysis","volume":"85","author":"Clohisy D","year":"2003","journal-title":"J Bone Joint Surg Am"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-0266(02)00133-X"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199274060-00006"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198365050-00001"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199807000-00004"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199902000-00018"},{"key":"e_1_2_1_16_2","first-page":"11","article-title":"Quantitative and qualitative analysis of polyethylene wear particles in synovial fluid of patients with total knee arthroplasty: a preliminary report","volume":"309","author":"Bosco J","year":"1994","journal-title":"Clin Orthop"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100130520"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.76B1.8300684"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.20102","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.20102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T19:52:26Z","timestamp":1700250746000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.20102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9,27]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["10.1002\/dc.20102"],"URL":"https:\/\/doi.org\/10.1002\/dc.20102","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,9,27]]}}}