{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:30:39Z","timestamp":1758123039645},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,8,2]],"date-time":"2005-08-02T00:00:00Z","timestamp":1122940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Paraspinal masses (PSM) are uncommon and present a wide spectrum of differential diagnoses on fine\u2010needle aspiration (FNA). We analyzed 59 cases of PSM on FNA in a 15\u2010yr period, in the context of clinicoradiologic correlation. Radiologic findings, clinical data, and tissue biopsies were reviewed. Patients were 14\u201383 yr of age (mean 54.7) with a M:F ratio of 1.36:1. Of the 59 cases, 39 (66%) were deemed diagnostic. Of these, 8 (21%) revealed nonneoplastic lesions and 31 (79%) yielded neoplasms: 2 (6%) benign and 29 (94%) malignant. Of the malignant cases, 22 (76%) were metastatic tumors from various sites, while 7 (24%) were cancers from local spread, which included non\u2010Hodgkin's lymphoma (NHL, 5) and myeloma (2). Benign neoplasms were nerve sheath tumors. Metastatic tumors consisted of adenocarcinoma, 9; squamous\u2010cell carcinoma, 3; renal\u2010cell carcinoma, 1; and non\u2010small\u2010cell carcinoma\/not otherwise specified (NOS), 9. Twenty\u2010four (41%) cases received further studies: immunoperoxidase (IPOX) alone, 17 (71%); special stains for microorganisms, 2 (8%); IPOX\/other special stains, 4 (17%); and flow cytometry analysis, 1 (4%). Eight (14%) cases received follow\u2010up biopsies. Half of these biopsies added information to previously \u201cnondiagnostic\u201d FNAs. Of the previously \u201cdiagnostic\u201d FNAs, tissue biopsy yielded no additional information. Cytopathologic diagnoses were consistent with the pre\u2010FNA radiology analyses in 13 (39%) cases. In instances of radiologic and cytopathologic discrepancy (4 cases, 12%), diagnoses made by FNA reversed the initial radiologic impression of neoplasm to infection, and vice versa. PSMs are rare lesions (0.26% of total FNAs done in 15 yr at our institution). The most common lesion encountered is metastatic adenocarcinoma, followed by NHL. Ancillary studies are helpful in difficult cases. In cases of radiologic\/cytopathologic discrepancy, FNA diagnoses are more accurate and decisive for patient management. The sensitivity and specificity of a PSM FNA are 88% and 75% respectively. Diagn. Cytopathol. 2005;33:157\u2013161. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.20319","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T20:23:43Z","timestamp":1123100623000},"page":"157-161","source":"Crossref","is-referenced-by-count":7,"title":["Cytopathologic analysis of paraspinal masses: A study of 59 cases with clinicoradiologic correlation"],"prefix":"10.1002","volume":"33","author":[{"given":"Julie M.","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila","family":"Sheth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Z.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,8,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.10.1155"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/122.1.111"},{"key":"e_1_2_1_4_2","first-page":"425","article-title":"Computed tomographic (CT)\u2010guided percutaneous fine\u2010needle aspiration biopsy: the Yale experience","volume":"59","author":"Hammers LW","year":"1986","journal-title":"Yale J Biol Med"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00588020"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/02841859909175570"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)62633-0"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000328605"},{"key":"e_1_2_1_9_2","first-page":"214","article-title":"Sonographically guided fine\u2010needle biopsy of peripheral lung tumors","volume":"30","author":"Mathis G","year":"1990","journal-title":"Radiologe"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000282308"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199705)16:5<392::AID-DC3>3.0.CO;2-E"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0339(200011)23:5<318::AID-DC6>3.0.CO;2-8"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199909000-00003"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000328543"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199802)18:2<137::AID-DC10>3.0.CO;2-M"},{"key":"e_1_2_1_16_2","first-page":"701","article-title":"Neuroblastoma and diagnostic imaging","volume":"22","author":"Sherazi ZA","year":"1993","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840020205"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1053\/adpa.2001.21479"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000332721"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0141-9854.2003.00546.x"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.65.2.210"},{"key":"e_1_2_1_22_2","first-page":"170","article-title":"Fine\u2010needle aspiration of thoracic extramedullary hematopoiesis","volume":"27","author":"Walker AN","year":"1983","journal-title":"Acta Cytol"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.154.4.2107698"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.20319","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.20319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T06:36:48Z","timestamp":1700203008000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.20319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,2]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["10.1002\/dc.20319"],"URL":"https:\/\/doi.org\/10.1002\/dc.20319","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8,2]]}}}