{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:28:14Z","timestamp":1765294094320},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,8,2]],"date-time":"2005-08-02T00:00:00Z","timestamp":1122940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Osteosarcoma, a primary malignant tumor of the long bones, frequently metastasizes to the lungs. We report an unusual case of osteosarcoma metastatic to the right adrenal gland in a 37\u2010yr\u2010old male who presented 8 yr after remission with an adrenal mass. A preoperative diagnosis was made by fine\u2010needle aspiration (FNA) biopsy. FNA biopsy revealed pleomorphic oval cells with prominent nucleoli, spindle cells, and giant tumor cells. Diagnostic osteoid was readily seen on smears and was also detected by polarization of cell\u2010block section. Immunocytochemical stains revealed positivity of tumor cells for vimentin and osteonectin. Cytokeratin stains were negative. The cytologic diagnosis of metastatic Osteosarcoma was made, which was later confirmed upon resection of tumor by histology. Although the role of FNA in the diagnosis of primary bone tumors, including osteogenic sarcoma (OGS), remains controversial, this case, however, demonstrates the value of FNA biopsy combined with immunocytochemistry performed on the aspirated material in diagnosing osteosarcoma from an unusual location such as the adrenal gland. Diagn. Cytopathol. 2005;33:201\u2013204. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.20335","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T20:29:56Z","timestamp":1123100996000},"page":"201-204","source":"Crossref","is-referenced-by-count":12,"title":["Osteosarcoma metastatic to adrenal gland diagnosed by fine\u2010needle aspiration"],"prefix":"10.1002","volume":"33","author":[{"given":"Noman H.","family":"Siddiqui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jigna","family":"Jani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,8,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-195739040-00002"},{"key":"e_1_2_1_3_2","first-page":"264","volume-title":"World health organization classification of tumors: tumors of soft tissue and bone","author":"Raymond AK","year":"2002"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/107327480100800303"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1950)3:1<74::AID-CNCR2820030111>3.0.CO;2-7"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.5858\/2000-124-1682-MOPAAS","article-title":"Metastatic osteosarcoma presenting as a small\u2010bowel polyp. A case report and review of the literature","volume":"124","author":"Panizo\u2010Santos A","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_7_2","first-page":"1694","article-title":"Renal metastasis from osteogenic sarcoma: report of a case","volume":"84","author":"Kajikawa T","year":"1993","journal-title":"Nippon Hinyokika Gakkai Zasshi"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/030089169207800617"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199508000-00024"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199903)20:3<131::AID-DC4>3.0.CO;2-T"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10196"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000331615"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/15513810109168610"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199602)14:1<51::AID-DC10>3.0.CO;2-C"},{"key":"e_1_2_1_15_2","first-page":"602","article-title":"Fine needle aspiration of bone tumors","volume":"24","author":"Agarwal S","year":"2000","journal-title":"Cancer Detect Prev"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1309\/YN14-K8U4-5FLJ-DGJE"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/112.2.179"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.20335","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.20335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T06:37:30Z","timestamp":1700203050000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.20335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,2]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["10.1002\/dc.20335"],"URL":"https:\/\/doi.org\/10.1002\/dc.20335","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8,2]]}}}