{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:32:55Z","timestamp":1770823975803,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2006,8,9]],"date-time":"2006-08-09T00:00:00Z","timestamp":1155081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe for the first time the cytologic features of mucinous spherulosis (MS), a variant of collagenous spherulosis (CS) of the breast characterized by cribiform structures containing lightly basophilic material, embedded in a loosely mucinous acellular background. Histologically, the lesion was part of a complex hyperplasia containing foci of sclerosing adenosis, and foci of atypical ductal hyperplasia (ADH). Immunohistochemical study showed reactivity with smooth muscle actin and focally for cytokeratin 14. Cytologic features of MS were recognized retrospectively and consisted of intermediate to large round hyaline spherules, naked or surrounded by myoepithelial cells. A fibrillary radial appearance was observed with Diff\u2010Quick stain.<\/jats:p><jats:p>We draw attention to the importance of recognizing these features because they can easily pose problems either by being overlooked or overdiagnosed as mucinous carcinoma. Differential diagnosis is briefly discussed. Diagn. Cytopathol. 2006;34:626\u2013630. \u00a9 2006 Wiley\u2013Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.20536","type":"journal-article","created":{"date-parts":[[2006,8,9]],"date-time":"2006-08-09T16:59:08Z","timestamp":1155142748000},"page":"626-630","source":"Crossref","is-referenced-by-count":6,"title":["A case of mucinous spherulosis of the breast diagnosed retrospectively in FNA material"],"prefix":"10.1002","volume":"34","author":[{"given":"Juan B.","family":"Laforga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198706000-00001"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199512000-00004"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.57.1.83"},{"key":"e_1_2_1_5_2","first-page":"626","article-title":"Spherulosis of the breast. 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Report of a case with diagnosis by fine needle aspiration biopsy with immunocytochemical and ultrastructural observations","volume":"37","author":"Highland KE","year":"1993","journal-title":"Acta Cytol"},{"key":"e_1_2_1_13_2","first-page":"725","article-title":"Diagnosis of collagenous spherulosis of the breast by fine needle aspiration cytology. A report of two cases","volume":"37","author":"Sola P\u00e9rez J","year":"1993","journal-title":"Acta Cytol"},{"key":"e_1_2_1_14_2","first-page":"1071","article-title":"Collagenous spherulosis of the breast diagnosed by fine needle aspiration biopsy","volume":"39","author":"Rey A","year":"1995","journal-title":"Acta Cytol"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000326537"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199605)14:4<328::AID-DC10>3.0.CO;2-M"},{"key":"e_1_2_1_17_2","first-page":"175","article-title":"Mucinous breast carcinoma and mixed mucinous\u2010infiltrating ductal carcinoma: A comparative cytologic study","volume":"10","author":"Stanley MW","year":"1994","journal-title":"Diagn Cytopathol"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/95.6.875"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02966714"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199905000-00009"},{"key":"e_1_2_1_21_2","first-page":"703","article-title":"Value of fine needle aspiration cytology of the breast, with an emphasis on the cytodiagnosis of colloid carcinoma","volume":"35","author":"Gupta RK","year":"1991","journal-title":"Acta Cytol"},{"key":"e_1_2_1_22_2","first-page":"247","article-title":"Pitfalls in fine needle aspiration cytology of breast tumors. 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