{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T10:49:31Z","timestamp":1769942971114,"version":"3.49.0"},"reference-count":11,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,2,15]],"date-time":"2007-02-15T00:00:00Z","timestamp":1171497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Breast cancer with signet\u2010ring cells is very rare. In this article, we present a case of invasive ductal carcinoma with signet\u2010ring cells and mucinous carcinoma components, which could be diagnosed as a primary cancer by immunocytochemical study of fine\u2010needle aspiration cytology material. A 73\u2010yr\u2010old Japanese woman noticed a palpable mass in the left breast. The aspiration cytology disclosed the monotonous proliferation of signet\u2010ring cell with cytological atypia. The immunocytochemical examination of neoplastic cells showed a positive reaction for estrogen receptor. The extensive examination of body before the operation did not disclose any tumors in other anatomic sites. The histological examination of surgically resected breast tumor showed invasive ductal carcinoma with foci of signet\u2010ring cell and mucinous carcinomas. Finally, our preliminary report suggests that immunocytochemical examination of aspiration cytology materials may provide useful information in searching the primary site of breast carcinoma with signet\u2010ring cells. Diagn. Cytopathol. 2007;35:171\u2013173. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.20609","type":"journal-article","created":{"date-parts":[[2007,2,15]],"date-time":"2007-02-15T18:14:41Z","timestamp":1171563281000},"page":"171-173","source":"Crossref","is-referenced-by-count":12,"title":["Invasive ductal carcinoma of the breast with signet\u2010ring cell and mucinous carcinoma components: Diagnostic utility of immunocytochemistry of signet\u2010ring cells in aspiration cytology materials"],"prefix":"10.1002","volume":"35","author":[{"given":"Naoto","family":"Kuroda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nokiaki","family":"Fujishima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Ohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hirouchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang\u2010Hong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,15]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197602)37:2<828::AID-CNCR2820370231>3.0.CO;2-N"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/ajcp\/73.1.31","article-title":"Signet\u2010ring cell carcinoma of the breast: A clinicopathologic study of 24 cases","volume":"71","author":"Hull M","year":"1980","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00430680"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850601)55:11<2533::AID-CNCR2820551103>3.0.CO;2-B"},{"key":"e_1_2_1_6_2","first-page":"245","article-title":"Signet\u2010ring cell variant of invasive lobular carcinoma of the breast: A clinicopathologic study of 11 cases","volume":"118","author":"Eltorky M","year":"1994","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_7_2","first-page":"64","article-title":"The significance of signet\u2010ring cells in infiltrating lobular carcinoma of the breast","volume":"119","author":"Frost AR","year":"1995","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2000.01007.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02967172"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1092-9134(99)80013-6"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1309\/A09ERYMFR64NERDW"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"799","DOI":"10.5858\/2006-130-799-MPISCC","article-title":"Mucin profiles in signet\u2010ring cell carcinoma","volume":"130","author":"Nguyen MD","year":"2006","journal-title":"Arch Pathol Lab Med"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.20609","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.20609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T04:18:00Z","timestamp":1700021880000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.20609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,15]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1002\/dc.20609"],"URL":"https:\/\/doi.org\/10.1002\/dc.20609","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,15]]}}}