{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T17:50:09Z","timestamp":1783792209442,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,3,12]],"date-time":"2009-03-12T00:00:00Z","timestamp":1236816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study was designed to assess the utility of fine\u2010needle aspiration cytology (FNAC) in the preoperative localization of parathyroid adenoma (PA). Fifty\u2010seven samples from fifty\u2010three cases of PA (four patients had bilateral disease) were obtained by ultrasound (US)\u2010guided fine\u2010needle aspiration. Parathyroid hormone (PTH) estimation was performed on the supernatant of the aspirated fluid on all cases. Subsequently, all of them underwent cytologic evaluation. The cytology slides were evaluated using the following criteria: Cellularity, architectural patterns, bare nuclei in the background, nuclear morphology, and background features (colloid\u2010like material or macrophages). Parathyroid cells were seen in 23 samples (40.4%). The cellularity of the smears was insufficient for interpretation in 16 samples (28.1%); and thyroid follicles and colloid were seen in 18 samples (31.5%). Majority of the samples with parathyroid cells showed moderate cellularity with monomorphous round to slightly oval cells predominantly arranged in loose two\u2010dimensional clusters with occasional papillary fragments. Majority of them exhibited a stippled nuclear chromatin. No significant pleomorphism, mitotic activity, or prominent nucleoli were observed. Most samples showed bare nuclei in the background. In conclusion, US\u2010guided FNAC has its limitations because of low sensitivity in primary localization of the parathyroid adenoma in cases of primary hyperparathyroidism and is not a useful mode of investigation in cases of PA. Diagn. Cytopathol. 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.21020","type":"journal-article","created":{"date-parts":[[2009,3,12]],"date-time":"2009-03-12T10:25:32Z","timestamp":1236853532000},"page":"407-410","source":"Crossref","is-referenced-by-count":48,"title":["Parathyroid fine\u2010needle aspiration cytology in the evaluation of parathyroid adenoma: Cytologic findings from 53 patients"],"prefix":"10.1002","volume":"37","author":[{"given":"Archana M.","family":"Agarwal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel S.","family":"Bentz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Hungerford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dev","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800820723"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.10.005"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000326305"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000327103"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9180-z"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000149451.45264.90"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2004.00858.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.134.8.824"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.171.3.9725323"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(95)90068-3"},{"key":"e_1_2_1_12_2","first-page":"728","article-title":"Fine needle aspiration cytology in the preoperative diagnosis of ultrasonically enlarged parathyroid glands","volume":"35","author":"Halbauer M","year":"1991","journal-title":"Acta Cytol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6413-3-6"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1989.tb00822.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22576"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199706)16:6<476::AID-DC2>3.0.CO;2-8"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20783"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.21020","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.21020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T03:03:13Z","timestamp":1699930993000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.21020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["10.1002\/dc.21020"],"URL":"https:\/\/doi.org\/10.1002\/dc.21020","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,12]]}}}