{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T12:36:21Z","timestamp":1711715781323},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2009,6,12]],"date-time":"2009-06-12T00:00:00Z","timestamp":1244764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Decidual reaction in pelvic lymph nodes has been increasingly documented during pregnancy. This may pose diagnostic difficulty during intraoperative frozen section (FS) and cytological consultation in women undergoing surgical procedures for cervical Squamous cell carcinoma (SCC). A 34\u2010year\u2010woman diagnosed to have invasive SCC (stage IB1) of the cervix at 14th week of her first pregnancy underwent abdominal radical trachelectomy and pelvic lymphadenectomy at 22 weeks of gestation. Cytological smears of two of the lymph nodes from intraoperative FS revealed isolated eosinophilic hyaline globules (HG) measuring 45\u201350 microns, in addition to large polygonal cells with amphophilic cytoplasm and hypochromatic nuclei and occasional squamous\u2010looking cells with atypical hyperchomatic nuclei. These findings posed a diagnostic dilemma at intraoperative consultation and no definitive diagnosis was rendered. The formlin\u2010fixed, paraffin\u2010embedded histological sections of the same lymph nodes showed ectopic decidua with no evidence of metastatic SCC. Decidual cells are a cause of concern for both cytologists and histopathologists. In pregnant women complicated by cervical cancer intraoperative evaluation of pelvic lymph nodes is of utmost importance in order to adopt the optimal conservative treatment modality. In the absence of clear cut evidence of malignancy, a diagnosis of metastatic SCC should not be rendered. Diagn. Cytopathol. 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.21113","type":"journal-article","created":{"date-parts":[[2009,6,15]],"date-time":"2009-06-15T18:24:13Z","timestamp":1245090253000},"page":"696-698","source":"Crossref","is-referenced-by-count":2,"title":["Hyaline globules in ectopic decidua in a pregnant woman with cervical squamous cell carcinoma"],"prefix":"10.1002","volume":"37","author":[{"given":"Muralee","family":"Dharan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,6,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"183","volume-title":"Koss' diagnostic cytology and its histopathologic basis","author":"Koss LG","year":"2006"},{"key":"e_1_2_1_3_2","first-page":"905","article-title":"Spectrum of cytologic changes in pregna\u2010ncy. A review of 100 abnormal cervicovaginal smears, with emphasis on diagnostic pitfalls","volume":"39","author":"Pisharody LR","year":"1995","journal-title":"Acta cytol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.5858\/2005-129-e117-EDOPLN","article-title":"Ectopic decidua of pelvic lymph nodes: A potential diagnostic pitfall","volume":"129","author":"Wu DC","year":"2005","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_5_2","first-page":"276","article-title":"Stage IB cervical cancer in a pregnant woman at 25 weeks of Gestation","volume":"29","author":"Gonzalez BE","year":"2008","journal-title":"Eur J Gynecol Oncol"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.03.025"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68181-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.12.006"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930260103"},{"key":"e_1_2_1_10_2","first-page":"499","article-title":"Radical hysterectomy for cervical carcinoma in a pregnant women\u2010 a case of decidua mimicking meta\u2010static carcinoma in pelvic lymph nodes","volume":"26","author":"Hogg R","year":"2005","journal-title":"Eur J Gynecol Oncol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90375-1"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930380215"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1993.tb01244.x"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.21113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.21113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T20:29:17Z","timestamp":1699907357000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.21113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,12]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.1002\/dc.21113"],"URL":"https:\/\/doi.org\/10.1002\/dc.21113","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,12]]}}}