{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:31:23Z","timestamp":1761964283961},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T00:00:00Z","timestamp":1287014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Blastomycosis is an uncommon disease caused by the dimorphic fungus Blastomyces dermatitidis. It can manifest as chronic pulmonary symptoms or disseminated disease. Only three previous cases of blastomycosis involving the thyroid have been reported, of which two were diagnosed by fine\u2010needle aspiration. We present a case of disseminated blastomycosis initially diagnosed by thyroid fine\u2010needle aspiration. Our case was a 47\u2010year\u2010old man with past medical history significant for diabetes, hyperlipidemia, and chronic pancreatitis who presented with a 2\u2010week history of fever, chills, rigors, constipation, and 10 pound weight loss. Abdominal CT revealed chronic pancreatitis and a calcified mass in the pancreas. Chest CT revealed a single 1.5\u20132 cm thyroid mass and innumerably small 2\u20103 mm pulmonary nodule bilaterally. Fine\u2010needle aspiration of the thyroid demonstrated 10\u201320 \u03bcm broad\u2010based budding yeasts with thick\u2010walled, refractile capsules amidst a background of granulomatous inflammation, and was diagnosed as a fungal infection consistent with blastomycosis. The patient was started on treatment with itraconazole based upon the FNA diagnosis. Concurrent lung biopsy demonstrated rare possible yeast forms on histology. A specimen from the lung was sent for culture, and was positive for B. dermatitidis, confirming the diagnosis. Disseminated blastomycosis rarely involves the thyroid. However, the thyroid is amenable to fine\u2010needle aspiration. Fungal and mycobacterial cultures and special stains for fungal organisms should be requested on all thyroid fine\u2010needle aspiration biopsies with granulomatous inflammation. Diagn. Cytopathol. 2011. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.21466","type":"journal-article","created":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T15:14:19Z","timestamp":1287069259000},"page":"446-450","source":"Crossref","is-referenced-by-count":6,"title":["Disseminated blastomycosis diagnosed by fine\u2010needle aspiration of the thyroid"],"prefix":"10.1002","volume":"39","author":[{"given":"Aaron M.","family":"Harvey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina R.","family":"Mody","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojgan","family":"Amrikachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,10,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(00)70254-3"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.4158\/EP.11.1.65"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.4158\/EP.14.2.224"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2007.0283"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-005-0239-3"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/ajot.2001.22588"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199810000-00009"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.10.3890-3891.2000"},{"key":"e_1_2_5_10_2","first-page":"427","article-title":"Initial diagnosis of disseminated cryptococcosis and acquired immunodeficiency syndrome by fine needle aspiration of the thyroid. A case report","volume":"38","author":"Kaw YT","year":"1994","journal-title":"Acta Cytol"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2007.01395.x"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.21466","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.21466","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:27:37Z","timestamp":1697444857000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.21466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,14]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1002\/dc.21466"],"URL":"https:\/\/doi.org\/10.1002\/dc.21466","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,14]]}}}