{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:46:05Z","timestamp":1760298365020},"reference-count":28,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2011,4,6]],"date-time":"2011-04-06T00:00:00Z","timestamp":1302048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Inflammatory myofibroblastic tumor (IMT) is an exquisitely rare neoplasm with a low incidence of metastasis. Previously, cytologic diagnosis of this entity, by fine needle aspiration (FNA) or endoscopic ultrasound guided fine needle aspiration (EUS\u2010FNA), was challenging, if not impossible. However, advancements in the field of molecular pathology, the applications of which have lagged in cytopathology relative to other disciplines, now makes diagnosis possible. Here we report a case of pulmonary inflammatory myofibroblastic tumor with mediastinal nodal metastasis in a 74\u2010year\u2010old man, definitively diagnosed by EUS\u2010FNA utilizing morphologic, immunohistochemical, and molecular findings, including fluorescent in situ hybridization studies for ALK gene rearrangement. This case report demonstrates the value of ancillary molecular studies to assist in the diagnosis of rare neoplasms, including those at sites of metastasis. Diagn. Cytopathol. 2012. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.21663","type":"journal-article","created":{"date-parts":[[2011,4,6]],"date-time":"2011-04-06T17:45:01Z","timestamp":1302111901000},"source":"Crossref","is-referenced-by-count":8,"title":["Metastatic inflammatory myofibroblastic tumor identified by EUS\u2010FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement"],"prefix":"10.1002","volume":"40","author":[{"given":"Samuel","family":"Borak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gene P.","family":"Siegal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishnu","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirag","family":"Jhala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darshana","family":"Jhala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,4,6]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2007.049387"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199508000-00001"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213393.57322.c7"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.06.021"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000325726"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-004-1170-6"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i26.3645"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-3-66"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880352"},{"key":"e_1_2_5_11_2","first-page":"91","volume-title":"Pathology and genetics of tumors of soft tissue and bone. 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