{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T09:33:46Z","timestamp":1783157626839,"version":"3.54.6"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,10,25]],"date-time":"2013-10-25T00:00:00Z","timestamp":1382659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:p>Cervical ectopy is common in adolescents, pregnant women, and those taking high doses of estrogen\u2010containing contraceptives. The majority of cases have spontaneous reversion, but some cases can be persistent. Studies suggested that the adequacy of a Pap smear could be affected and there is an increased risk cervical infections. This study is a cross\u2010sectional study conducted from December 2009 to February 2011 with 457 women with cervical ectopy and 736 without ectopy. Cervical samples were collected in vials for analysis by ThinPrep cytology (Hologic, Marlborough, MA). The Mann\u2013Whitney test and Fisher's exact test (95% CI) were applied. The study was approved by the ethics committee of the Federal University of Cear\u00e1. The mean ages of the study group and control group were 28.7 (\u00b114.8) and 33.6 (\u00b17.5) years old, respectively (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). Negative diagnosis for malignancy and intraepithelial lesion was present in 399 (87%) cases and 705 (96%) in the study and control groups, respectively (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). Shift in the flora suggestive of bacterial vaginosis (BV) was observed more frequently in the study group: 74 (16.2%) than in the control group: 86(11.7%) (<jats:italic>P<\/jats:italic>\u2009=\u20090.017). The differences among the other morphotypes showed no significance. The smears were atypical in 12.7% (58\/457) of the patients from the study group and in 4.2% (31\/736) in the control group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001; RR\u2009=\u20093 [2.033\u20134.712]). The association between ectopy and inflammatory cytology, the presence of the shift in the flora suggestive of BV and cytological atypia is evident. Diagn. Cytopathol 2014;42:401\u2013404. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.23053","type":"journal-article","created":{"date-parts":[[2013,10,25]],"date-time":"2013-10-25T18:37:24Z","timestamp":1382726244000},"page":"401-404","source":"Crossref","is-referenced-by-count":13,"title":["Uterine cervical ectopy during reproductive age: Cytological and microbiological findings"],"prefix":"10.1002","volume":"42","author":[{"given":"Jos\u00e9 Eleut\u00e9rio","family":"Junior","sequence":"first","affiliation":[{"name":"Maternal and Child Health Department Federal University of Cear\u00e1 Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo C\u00e9sar","family":"Giraldo","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department State University of Campinas Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Katherine Silveira","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department Federal University of Rio Grande do Norte Natal Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose Luce Gomes","family":"do Amaral","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department State University of Campinas Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iara Moreno","family":"Linhares","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-31802008000200014"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0512"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/319261"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/170.2.313"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)90279-1"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/oxfordjournals.aje.a116840","article-title":"Selective screening for Chlamydia trachomatis infection in a primary care population of women","volume":"138","author":"Stergachis A","year":"1993","journal-title":"Am J Epidemiol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-200210000-00007"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2003.10.002"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443619609007753"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19990301)85:5<1139::AID-CNCR18>3.0.CO;2-8"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.48.5.408"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2114"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)80021-X"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(99)00037-5"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199904)20:4<199::AID-DC3>3.0.CO;2-2"},{"key":"e_1_2_5_17_1","first-page":"305","article-title":"The association between sexually transmitted diseases and inflammatory cervical cytology","volume":"68","author":"Dimian C","year":"1992","journal-title":"Genitourin Med"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1783\/147118906776276440"},{"key":"e_1_2_5_19_1","first-page":"317","article-title":"Chlamydia trachomatis in sexually active teenage girls","volume":"67","author":"Rahm VA","year":"1991","journal-title":"Factors related to genital chlamydial infection: A prospective study. 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