{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:08:30Z","timestamp":1784120910222,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T00:00:00Z","timestamp":1387497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>Squamous\u2010lined cysts (SLC) in the pancreas are rare and include lymphoepithelial cysts (LEC), dermoid cysts (DC), and epidermoid cysts in heterotopic spleen (EC). Previously only rare case reports and small case series have been published describing the FNA findings in these entities. The departmental archives were searched for surgically excised SLC from the pancreas. Twenty\u2010five specimens were identified: 20 LEC, four EC, and one DC. Eight corresponding FNA specimens taken prior to resection were identified and available for review: seven LEC and one EC. A junior and senior pathologist reviewed the cases individually and then together for consensus. On morphological review, all lesions contained single nucleated and anucleated mature squamous cells, macrophages, and varying amounts of lymphocytes. Benign squamous fragments were found in half of all specimens. Amorphous debris was found in all cases. Keratin was found in all but two cases and its appearance varied among cases. Half of all cases contained cholesterol crystals. No nuclear atypia or necrosis was noted. Inspissated mucin, a potentially misleading finding, was seen in three cases. The most important goal in evaluating pancreatic cystic lesions is to exclude a mucin\u2010producing neoplasm. If features of a SLC are present, the differential diagnosis should include LEC, DC, and EC. Only 38% (3\/8) cases had the most specific features of an SLC present (squamous fragments, cholesterol crystals, keratin, and squamous cells), which suggests that most cases will not be specifically identified on FNA even by experienced cytopathologists. Diagn. Cytopathol. 2014;42:592\u2013599. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.23080","type":"journal-article","created":{"date-parts":[[2013,12,21]],"date-time":"2013-12-21T00:16:04Z","timestamp":1387584964000},"page":"592-599","source":"Crossref","is-referenced-by-count":17,"title":["Fine\u2010needle aspiration of squamous\u2010lined cysts of the pancreas"],"prefix":"10.1002","volume":"42","author":[{"given":"Christopher J.","family":"VandenBussche","sequence":"first","affiliation":[{"name":"Department of Pathology The Johns Hopkins Medical Institutions Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Maleki","sequence":"additional","affiliation":[{"name":"Department of Pathology The Johns Hopkins Medical Institutions Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,20]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"56","article-title":"Squamous\u2010lined cysts of the pancreas: lymphoepithelial cysts, dermoid cysts (teratomas), and accessory\u2010splenic epidermoid cysts","volume":"17","author":"Adsay NV","year":"2000","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5858\/133.3.388"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12253-009-9229-y"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0b013e3181359e36"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21185"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20865"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22289"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840090117"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199906)20:6<371::AID-DC8>3.0.CO;2-S"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199911)21:5<346::AID-DC10>3.0.CO;2-I"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.02.044"},{"key":"e_1_2_6_13_1","volume-title":"Cytology: Diagnostic Principles and Clinical Correlates","author":"Cibas ES","year":"2009"},{"key":"e_1_2_6_14_1","volume-title":"Atlas of Pancreatic Cytopathology with Histopathologic Correlations","author":"Ali SZ","year":"2009"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1309\/MFRFJ0XYJLN8NVDP"},{"key":"e_1_2_6_16_1","first-page":"398","article-title":"Intraductal papillary\u2010mucinous neoplasm of the pancreas","volume":"120","author":"Stelow EB","year":"2003","journal-title":"The findings and limitations of cytologic samples obtained by endoscopic ultrasound\u2010guided fine\u2010needle aspiration. 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