{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T05:40:52Z","timestamp":1696570852023},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T00:00:00Z","timestamp":1392681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>Different noncellular elements, such as round concentric calcified laminated structures, may be found in sputum smears. If these structures appear isolated on the background of the smear, the term usually used to describe them is \u201ccalcareous concretions\u201d (CC). On the contrary, when the structures are part of epithelial cell groups or small tissue fragments, the term used to describe them is \u201cPsammoma bodies\u201d (PB). The aim of this work is to establish the relationship between these structures and pulmonary disease, especially lung carcinoma, by searching for the presence of CC and\/or PB in sputum smears. Our study has taken as a basis 16.716 sputum smears from 696 patients obtained during a 7\u2010year period (2003\u20132009). After reviewing them, it was found that from the total, 66 cases (0.39%) contained round calcified structures, 57 of them (0.34%) corresponding to CC, and the remaining 9 ones (0.05%) corresponding to PB. From these 57 CC cases, 56 corresponded to benign entities, and only one was found with lung carcinoma. On the other hand, from the 9 PB cases all of them (100%) were related to lung adenocarcinoma. We conclude that, even having a similar morphological structure, these aforementioned calcified structures we have observed in sputum smears have different and relevant clinical significance. Diagn. Cytopathol. 2014;42:759\u2013765. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.23120","type":"journal-article","created":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T13:41:18Z","timestamp":1392730878000},"page":"759-765","source":"Crossref","is-referenced-by-count":6,"title":["Calcareous concretions and psammoma bodies in sputum smears: Do these similar structures have different clinical significance?"],"prefix":"10.1002","volume":"42","author":[{"given":"Rafael","family":"Mart\u00ednez\u2010Gir\u00f3n","sequence":"first","affiliation":[{"name":"CFGS Anatom\u00eda Patol\u00f3gica y Citolog\u00eda Instituto de Piedras Blancas Asturias Spain"},{"name":"Fundaci\u00f3n INCL\u00cdNICA Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Mart\u00ednez\u2010Torre","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Universidad de Oviedo Oviedo 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