{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T06:40:37Z","timestamp":1696574437388},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T00:00:00Z","timestamp":1436832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Swiss Embassy in Khartoum (Small Action Fund, 2013)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Breast lesions including breast cancer represent a major public health issue in Sudan. Fine\u2010needle aspiration cytology (FNAC) is an established, simple, highly accurate, minimally invasive, and cost\u2010effective method of diagnosing most breast lesions. The aim of this study is to document the most common breast conditions diagnosed by means of FNAC over a two\u2010year period in Atbara, a city in north Sudan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective, descriptive, cross\u2010sectional, laboratory\u2010based study in which records of all palpable breast lesions diagnosed by FNAC in the years 2012 and 2013 were reviewed and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The total number of cases studied was 232; most subjects, 222 (95.7%), were females. The age range was 15\u201390 years (mean 38.2). Painless lump was the most common 190 (81.9%) clinical presentation. The left breast was affected more often than the right breast, 56.0% vs. 40.5%. Benign conditions were 167 (72%). Malignant neoplasms were 65 (28.0%). The most important associations with malignancy were female sex, age above 35 years, multiparity, painless lump at upper outer quadrant of left breast, lump size above 2 cm and the presence of an enlarged ipsilateral axillary lymph node at presentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the northern part of Sudan, the prevalence of malignant breast lesions diagnosed by FNAC is more than one fourth of all cases presenting with palpable breast lumps. FNAC is a technique that is ideal for use in resource\u2010limited health settings. Diagn. Cytopathol. 2015;43:825\u2013829. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.23320","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T15:01:38Z","timestamp":1436886098000},"page":"825-829","source":"Crossref","is-referenced-by-count":1,"title":["Cytomorphology of palpable breast lesions: Diagnostic utility of <scp>FNAC<\/scp> in a developing country"],"prefix":"10.1002","volume":"43","author":[{"given":"Wadie M.","family":"Elmadhoun","sequence":"first","affiliation":[{"name":"Department of Pathology Nile Valley University Atbara Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed O.","family":"Almobarak","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine, University of Medical Sciences and Technology Khartoum Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelrahman M.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Pathology Najran University  Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarra","family":"Bushara","sequence":"additional","affiliation":[{"name":"Department of Medicine Nile Valley University Atbara Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sufian K.","family":"Noor","sequence":"additional","affiliation":[{"name":"Department of Medicine Nile Valley University Atbara Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazik Elmalaika O.S.","family":"Husain","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine and Health Sciences, Omdurman Islamic University Khartoum Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed H.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Medicine Milton Keynes University Hospital NHS Foundation Trust Buckinghamshire United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(97)00192-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.05.2308"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-509X.58854"},{"key":"e_1_2_6_5_1","first-page":"333","article-title":"Accuracy of combined clinical findings and fine needle aspiration cytology for the diagnosis in palpable breast tumors","volume":"51","author":"Carrillo JF","year":"1999","journal-title":"Rev Invest Clin"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.8.3411"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/01913123.2011.576327"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.5455\/ijmsph.2013.191120134"},{"key":"e_1_2_6_9_1","first-page":"48","article-title":"Evaluation of triple assessment modalities in the management of palpable breast lumps","volume":"9","author":"Saleem KN.","year":"2010","journal-title":"Iraqi Postgrad Med J"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.1994.tb00437.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21115"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP8BYTCFI0XJZU"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333969"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/695024"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/547580"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13187-011-0282-3"},{"key":"e_1_2_6_17_1","unstructured":"NilssonC.Characterization of male breast cancer: From molecule to clinical outcome. 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