{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:51:42Z","timestamp":1787496702447,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T00:00:00Z","timestamp":1455580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although the incidence of glandular epithelial abnormalities on cervical cytology is low, the clinical and histologic findings are often significant. The laboratory's 12\u2010year experience is reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      from January 1, 2003 to December 31, 2014, the Cytopathology Laboratory of the University of Wisconsin Hospital and Clinics processed 191,087 ThinPrep\n                      <jats:sup>\n                        <jats:bold>\u00ae<\/jats:bold>\n                      <\/jats:sup>\n                      Pap Tests of which 184 (0.1%) were reported as glandular epithelial abnormalities. One hundred forty\u2010three (78%) of these cases had histologic follow\u2010up and form the basis of this study. Of the 143 women (mean age, 52; median, 50), 45% presented with vaginal bleeding and 55% were asymptomatic. The cytologic groups included atypical glandular cells, atypical glandular cells; favor a neoplastic process, atypical endocervical cells, atypical endocervical cells; favor a neoplastic process, endocervical adenocarcinoma in situ, atypical endometrial cells and adenocarcinoma, NOS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, the histologic follow\u2010up showed epithelial abnormalities including endometrial and endocervical carcinoma, endocervical adenocarcinoma in situ, CIN 3 involving endocervical glands and metastatic carcinoma in 78% of the cases. The diagnoses were age\u2010dependent and influenced by clinical symptomatology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Glandular epithelial abnormalities on Pap tests warrant further clinical investigation. Diagn. Cytopathol. 2016;44:389\u2013393. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dc.23452","type":"journal-article","created":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T06:08:48Z","timestamp":1455602928000},"page":"389-393","source":"Crossref","is-referenced-by-count":18,"title":["Glandular epithelial abnormalities on thinprep\n                    <sup>\u00ae<\/sup>\n                    pap tests: Clinical and cytohistologic correlation"],"prefix":"10.1002","volume":"44","author":[{"given":"Suzanne M.","family":"Selvaggi","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Wisconsin School of Medicine and Public Health Madison Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00659-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199307000-00002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000328530"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.5468\/OGS.2013.56.2.76"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-2042-8"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/101.6.708"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840130515"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1996.0270"},{"key":"e_1_2_5_10_1","first-page":"523","article-title":"Cervical biopsy\u2010cytology correlation","volume":"120","author":"Jones BA","year":"1996","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/104.5.574"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1092-9134(98)80024-5"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000331080"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(99)90143-0"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20000825)90:4<207::AID-CNCR2>3.0.CO;2-H"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10070"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010225)93:1<1::AID-CNCR9000>3.0.CO;2-7"},{"key":"e_1_2_5_18_1","first-page":"616","article-title":"Ectopic decidual reaction of the uterine cervix. 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