{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T12:47:36Z","timestamp":1767703656556},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,7,29]],"date-time":"2016-07-29T00:00:00Z","timestamp":1469750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Myoepithelioma is a rare and usually benign salivary gland tumor derived from myoepithelial cells. Variability in cellular morphology and stromal composition leads to diagnostic pitfalls on fine\u2010needle aspiration cytology; therefore, histology and immunohistochemistry are often required for definitive diagnosis. We describe a case of parotid gland myoepithelioma in a 76\u2010year\u2010old woman, which was discovered incidentally on cerebral magnetic resonance imaging. Fine\u2010needle aspiration sampled cohesive aggregates of spindle\u2010shaped cells embedded in a fibrillary matrix as well as abundant mature adipocytes, initially considered as part of normal salivary gland parenchyma. Histology of the resected specimen showed bundles of spindle\u2010shaped cells embedded in loose connective tissue, admixed with numerous intralesional adipocytes. Immunohistochemical studies revealed a diffuse expression of p63 by this adipocytic population, an observation clearly indicating that myoepithelial cells can trans\u2010differentiate and acquire the morphology of mature adipocytes. Knowledge of this phenomenon can be helpful in the work\u2010up of salivary gland lesions. Diagn. Cytopathol. 2016;44:1090\u20131093. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.23550","type":"journal-article","created":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T13:32:06Z","timestamp":1479130326000},"page":"1090-1093","source":"Crossref","is-referenced-by-count":6,"title":["Myoepithelioma of the parotid gland with extensive adipocytic metaplasia: Report of a case with intriguing aspects on fine needle aspiration and p63 immunohistochemical expression"],"prefix":"10.1002","volume":"44","author":[{"given":"Vanessa","family":"Schneider","sequence":"first","affiliation":[{"name":"Institute of Pathology, University Hospital Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Nobile","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University Hospital Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertrand","family":"Duvoisin","sequence":"additional","affiliation":[{"name":"Medical Imaging Caroline Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Saglietti","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University Hospital Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Bongiovanni","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University Hospital Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,29]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"123","volume-title":"AFIP atlas of tumor pathology","author":"Ellis GL","year":"2008"},{"key":"e_1_2_4_3_1","first-page":"259","volume-title":"Pathology and genetics of head and neck tumors (WHO classification of tumors)","author":"Cardesa A","year":"2005"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000354958"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333563"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000326098"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23161"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0339(200010)23:4<253::AID-DC8>3.0.CO;2-0"},{"key":"e_1_2_4_9_1","first-page":"5","article-title":"Fine needle aspiration cytology in diagnosis of salivary gland lesions: A study with histologic comparison","volume":"10","author":"Jain R","year":"2013","journal-title":"Cytojournal"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215540305100201"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21444"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000168509.47243.4b"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004280100469"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2001.01054.x"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(83)80302-5"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890070509"},{"key":"e_1_2_4_17_1","article-title":"A case report of spindle cell myoepithelioma with extensive lipomatous metaplasia and thick collagen bundles in the submandibular gland","author":"Kwon MJ","journal-title":"Diagn Cytopathol."}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.23550","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.23550","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.23550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:41:20Z","timestamp":1695472880000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.23550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,29]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1002\/dc.23550"],"URL":"https:\/\/doi.org\/10.1002\/dc.23550","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,29]]}}}