{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T01:12:07Z","timestamp":1776561127395,"version":"3.51.2"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T00:00:00Z","timestamp":1486684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p>Xp11 translocation renal cell carcinoma (RCC) is a specific type of renal cell carcinoma recently placed under the \u201cMiT family translocation RCC\u201d at the last 2013 ISUP Vancouver classification of renal neoplasia. This tumor contains variable proportions of clear cells and could easily mimic papillary RCC, clear cell type, and clear cell papillary RCC. Given the small number of published cytologic findings of this tumor, it could easily present as a diagnostic pitfall. We describe a case of a 23\u2010year\u2010old man with a history of prior nephrectomy who presented with multiple mediastinal lymphadenopathies on imaging surveillance follow\u2010up. Fine\u2010needle aspiration of the lymph node showed tumor cells with voluminous clear to eosinophilic cytoplasm, well\u2010defined cell borders and hyperchromatic nuclei arranged in papillary architecture. Review of the prior nephrectomy specimen showed papillary cores surrounded by cells with voluminous clear to finely granular eosinophilic cytoplasm and distinct cell borders. Immunohistochemical stains performed on the nephrectomy specimen showed tumor positivity for CD10, E\u2010cadherin, a\u2010methylacyl coenzyme A racemase, and TFE3 supporting the diagnosis of Xp11 translocation renal cell carcinoma. Although this tumor was initially described predominantly in children, it could also occur in adults, as seen in this case. Familiarity with the cytologic findings of this tumor, use of immunohistochemical stains, or cytogenetic test to determine the type of gene fusion will be extremely useful in arriving at the correct diagnosis. Diagn. Cytopathol. 2017;45:456\u2013462. \u00a9 2017 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.23676","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T05:12:51Z","timestamp":1486703571000},"page":"456-462","source":"Crossref","is-referenced-by-count":13,"title":["Fine\u2010needle aspiration findings of <scp>X<\/scp>p11 translocation renal cell carcinoma metastatic to a hilar lymph node"],"prefix":"10.1002","volume":"45","author":[{"given":"Reima","family":"El Naili","sequence":"first","affiliation":[{"name":"Department of Pathology University of Texas Health Science Center San Antonio Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlo","family":"Nicolas","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Texas Health Science Center San Antonio Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Gorena","sequence":"additional","affiliation":[{"name":"Pathology Group of Louisiana Baton Rouge Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0375-1964","authenticated-orcid":false,"given":"Maria Luisa C.","family":"Policarpio\u2010Nicolas","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,10]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"378","volume-title":"Pathology and genetics of tumours of the urinary system and male genital organs (World Health Organization Classification of Tumours)","author":"Argani PL.","year":"2004"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2015.02.003"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-1183"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31828a69ae"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20523"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20548"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000325531"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000366406"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12208"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000325412"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/00313021003767348"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181dd577e"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e8ce5b"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2009.58"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0283-CC"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19981025)84:5<303::AID-CNCR6>3.0.CO;2-7"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20546"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2008.00593.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21779"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181f2ee0b"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31824dd972"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2013.208"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20571"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2014.12.008"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.23676","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.23676","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T19:29:05Z","timestamp":1695497345000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.23676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,10]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1002\/dc.23676"],"URL":"https:\/\/doi.org\/10.1002\/dc.23676","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,10]]}}}