{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:33:36Z","timestamp":1777419216828,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T00:00:00Z","timestamp":1491868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Montefiore Medical Center, Albert Einstein College of Medicine"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe a case of a 41\u2010year old male patient with no significant prior medical history who presents with symptoms of Transient Ischemic Attack and stroke. Magnetic Resonance Imaging (MRI) of the brain identified areas of ischemia in the left side, and angiography showed occlusion of the left Medial Cerebral Artery (MCA). Cardiac Transthoracic Echocardiogram (TTE) for stroke evaluation incidentally noted a mediastinal abnormality leading to cancer work\u2010up. Computer Tomography (CT) and <jats:sup>18<\/jats:sup>F\u2010fluorodeoxyglucose (FDG) PET\u2010CT scan of the chest incidentally revealed an avid 6 cm paraesophagial\/subcarinal mass. Further diagnostic work\u2010up with endoscopic and endobronchial ultra sound (EBUS)\u2010guided fine needle aspiration (FNA) of the mass yielded a cytology diagnosis of Germ Cell Tumor (GCT), with choriocarcinoma component. Additionally, high plasma levels of \u03b2\u2010human chorionic gonadotrophin (\u03b2\u2010HCG) were detected with no evidence of testicular tumor. This exceedingly rare presentation for a primary mediastinal choriocarcinoma underscores the importance of complete investigation of young patients presenting with neurological symptoms compatible with ischemic events. Diagn. Cytopathol. 2017;45:738\u2013743. \u00a9 2017 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/dc.23719","type":"journal-article","created":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T05:06:57Z","timestamp":1491887217000},"page":"738-743","source":"Crossref","is-referenced-by-count":12,"title":["Incidental primary mediastinal choriocarcinoma diagnosed by endobronchial ultrasound\u2010guided fine needle aspiration in a patient presenting with transient ischemic attack and stroke"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5764-5454","authenticated-orcid":false,"given":"Ivo M. 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M.","family":"Farinhas","sequence":"additional","affiliation":[{"name":"Department of NeuroRadiology Albert Einstein College of Medicine, Montefiore Medical Center Bronx New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samer","family":"Khader","sequence":"additional","affiliation":[{"name":"Department of Pathology Albert Einstein College of Medicine, Montefiore Medical Center Bronx New York"},{"name":"Division of Cytology Albert Einstein College of Medicine, Montefiore Medical Center Bronx New 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