{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:57:12Z","timestamp":1773277032053,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T00:00:00Z","timestamp":1510272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Calcitonin\u2010secreting neuroendocrine tumors are rare and have been reported in literature as case reports or case series in various organs including lung, pancreas, larynx, bladder, and ovary. These tumors have similar cytologic features and immunohistochemical profile to medullary thyroid carcinoma and thus it is difficult to distinguish them, especially when calcitonin\u2010secreting neuroendocrine tumors are intermediate or higher grade and there is a mass lesion in the thyroid gland. Here, we report a rare case of calcitonin secreting atypical carcinoid tumor of the lung in a patient with thyroid nodule. However, after extensive ancillary studies on the thyroid gland, no tumor was detected and subsequent resection specimen revealed a pulmonary atypical carcinoid tumor with metastasis to level 11 lymph node. Being aware of this entity has significant clinical, diagnostic, and therapeutic implications and can prevent unnecessary thyroidectomies with subsequent possible morbidities.<\/jats:p>","DOI":"10.1002\/dc.23852","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T07:46:42Z","timestamp":1510300002000},"page":"345-348","source":"Crossref","is-referenced-by-count":15,"title":["Metastatic medullary thyroid carcinoma or calcitonin\u2010secreting carcinoid tumor of lung? A diagnostic dilemma in a patient with lung mass and thyroid nodule"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9439-0294","authenticated-orcid":false,"given":"Shifteh","family":"Vahidi","sequence":"first","affiliation":[{"name":"Cytopathology Fellow, University of Minnesota Minneapolis 55455"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmie","family":"Stewart","sequence":"additional","affiliation":[{"name":"Associate Professor of Pathology, University of Minnesota Minneapolis 55455"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Amin","sequence":"additional","affiliation":[{"name":"Associate Professor of Pathology, University of Minnesota Minneapolis 55455"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilian","family":"Racila","sequence":"additional","affiliation":[{"name":"Associate Professor of Pathology, University of Minnesota Minneapolis 55455"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faqian","family":"Li","sequence":"additional","affiliation":[{"name":"Professor of Pathology, University of Minnesota Minneapolis 55455"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1530\/EJE-15-0917","article-title":"Neuroendocrine tumors producing calcitonin: characteristics, prognosis and potential interest of calcitonin monitoring during follow\u2010up","volume":"174","author":"Nozi\u00e8res C","year":"2016","journal-title":"Eur J Endocrinol."},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01600272"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002419"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0b013e3182015f5d"},{"key":"e_1_2_4_6_1","first-page":"606389","article-title":"Calcitonin\u2010Secreting neuroendocrine tumors of larynx with metastasis to thyroid","volume":"2015","author":"Labryer L","year":"2015","journal-title":"Case Rep Endocrinol."},{"key":"e_1_2_4_7_1","doi-asserted-by":"crossref","DOI":"10.1177\/014556131509400104","article-title":"Primary calcitonin\u2010secreting neuroendocrine carcinoma of the supraglottic larynx","volume":"94","author":"Hakeem A","year":"2015","journal-title":"Ear Nose Throat J."},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-5-88"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(79)80010-6"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2016.11.2222"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/019021401317138487"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2016.02.003"},{"key":"e_1_2_4_13_1","unstructured":"TravisWD BrambillaE BurkeAP MarxA NocholsonA.WHO classification of tumors of the lung pleura thymus and heart. Lyon: WHO. International Agency for Research on Cancer (IARC); 2015;412."},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-10-0111"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1981.tb01785.x"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01600306"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089169307900315"},{"key":"e_1_2_4_18_1","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1055\/s-0029-1231083","article-title":"Differentiation between thyroidal and ectopic calcitonin secretion in patients with coincidental thyroid nodules and pancreatic tumors\u2010 A report of two cases","volume":"118","author":"Schneider R","year":"2009","journal-title":"Exp Clin Endocrinol Diabetes."}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.23852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.23852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:48:04Z","timestamp":1695552484000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.23852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,10]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1002\/dc.23852"],"URL":"https:\/\/doi.org\/10.1002\/dc.23852","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,10]]}}}