{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:54:28Z","timestamp":1757703268790,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,16]],"date-time":"2018-11-16T00:00:00Z","timestamp":1542326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>According to the American Society of Colposcopy and Cervical Pathology (ASCCP), cervical cytology patients who test positive for atypical squamous cells of undetermined significance (ASCUS) and the human papilloma virus (HPV) positive are recommended to undergo colposcopies. This study compared the colposcopic biopsy evaluation results of patients with positive cervical cytology results for ASCUS and HPV with regards to their HPV genotypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study included 179 patients who underwent cervical cancer screening tests between June 2015 and June 2017 and whose results displayed positive cervical cervical cytology results for ASCUS and HPV. Cytological samples were classified using the Bethesda system in liquid\u2010based specimens. The Hybrid Capture II system was used to define the HPV\u2010DNA. Colposcopic diagnoses and biopsy results were compared in terms of the outcomes of the Pap test and HPV genotypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 107 ASCUS\/HPV16\/18\u2010positive patients. Of the HPV 16\/18 positive patients; 28 (26.1%) patients were detected with CIN1, 8 (7.5%) patients were detected with CIN2, 6 (6%) patients were detected with CIN3, and 1 (0.9%) patient was detected with cervical cancer. Of the 72 non\u2010HPV 16\u201018 positive patients; 8 (11%) patients were detected with CIN1 and 2 (2.7%) patients were detected with CIN2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study believes that the ASCCP recommendations, which state that a \u2018colposcopy should be performed on all women with positive cytology for ASCUS\/non\u2010HPV16\/18 oncogenic types\u2019, is required to be revised. This will reduce the rate of the colposcopy procedures by 40% in women with ASCUS\/HPV positivity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24029","type":"journal-article","created":{"date-parts":[[2018,11,16]],"date-time":"2018-11-16T14:50:04Z","timestamp":1542379804000},"page":"105-109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Does the \u2018equal management of equal risks\u2019 model cause overtreatment in patients with positive cervical cytology results for ASCUS\/non\u2010HPV16\/18 oncogenic types?"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5652-3423","authenticated-orcid":false,"given":"\u0130brahim","family":"Karaca","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cihan","family":"Comba","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6khan","family":"Demirayak","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7976-8287","authenticated-orcid":false,"given":"\u015eakir Vokan","family":"Erdo\u011fan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Ho\u015fg\u00f6ren","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130sa Aykut","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,11,16]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"536495","article-title":"Evaluation of the oncogenic human papillomavirus DNA test with liquid\u2010based cytology in primary cervical cancer screening and the importance of the ASC\/SIL ratio: a Belgian study","volume":"18","author":"Catteau X","year":"2014","journal-title":"ISRN Obstet Gynecol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e318287d329"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.18.2382"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.17.1881"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPZ5JY6FCVNMOT"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e318285423c"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2008.00631.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2005.07.033"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e31825c31dd"},{"key":"e_1_2_8_11_1","first-page":"8054","article-title":"Martin\u2010Hirsch PP. 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