{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T16:23:57Z","timestamp":1775060637540,"version":"3.50.1"},"reference-count":8,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T00:00:00Z","timestamp":1553558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>The occurrence of lupus erythematosus cells (LE cells) in serous body fluids is extremely uncommon but, when present, is highly specific for systemic lupus erythematosus (SLE). LE cells are commonly reported in pleural and peritoneal effusions but very rarely documented in pericardial effusion. Here, we report a case in which pericardial fluid examination clinched the diagnosis of SLE which was clinically suspected of tuberculosis\/hypothyroid effusion by striking presence of LE cells on May\u2010Gr\u00fcnwald Giemsa\u2010stained and Papanicolaou stained smears. Subsequent serologic studies revealed high titers of anti\u2010nuclear antibodies and anti\u2010ds\u2010DNA confirming the diagnosis of SLE. This case highlights the importance of careful examination of pericardial fluid or pleural or peritoneal fluid in the diagnosis of unsuspected cases of SLE in an era wherein \u201cLE cell detection\u201d is considered to be of historic interest.<\/jats:p>","DOI":"10.1002\/dc.24176","type":"journal-article","created":{"date-parts":[[2019,3,26]],"date-time":"2019-03-26T15:04:21Z","timestamp":1553612661000},"page":"740-742","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["SLE pericardial effusion clinically mimicking hypothyroidism and tuberculosis diagnosed on cytology with LE cells"],"prefix":"10.1002","volume":"47","author":[{"given":"Bidish K.","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Pathology Jawaharlal Institute of Postgraduate Medical Education and Research  Puducherry\u2010605006"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3880-9150","authenticated-orcid":false,"given":"Debasis","family":"Gochhait","sequence":"additional","affiliation":[{"name":"Department of Pathology Jawaharlal Institute of Postgraduate Medical Education and Research  Puducherry\u2010605006"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norton","family":"Stephen","sequence":"additional","affiliation":[{"name":"Department of Pathology Jawaharlal Institute of Postgraduate Medical Education and Research  Puducherry\u2010605006"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neelaiah","family":"Siddaraju","sequence":"additional","affiliation":[{"name":"Department of Pathology Jawaharlal Institute of Postgraduate Medical Education and Research  Puducherry\u2010605006"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,26]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"25","article-title":"Presentation of two bone marrow elements; the \u2018tart\u2019 cell and \u2018LE\u2019 cell","volume":"23","author":"Hargraves MM","year":"1948","journal-title":"Proc Staff Meet Mayo Clin"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.1992.tb00014.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel308"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1952.72930190010009e"},{"key":"e_1_2_7_6_1","first-page":"1331","article-title":"Lupus pericarditis","volume":"111","author":"Wolcove N","year":"1975","journal-title":"Can Med Assoc J"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20758"},{"key":"e_1_2_7_8_1","first-page":"553","article-title":"Pleural effusion in systemic lupus erythematosus","volume":"24","author":"Reda MG","year":"1980","journal-title":"Acta Cytol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.15.3.211"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24176","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T17:59:19Z","timestamp":1694368759000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,26]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1002\/dc.24176"],"URL":"https:\/\/doi.org\/10.1002\/dc.24176","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,26]]},"assertion":[{"value":"2018-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}