{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:59:59Z","timestamp":1768798799555,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T00:00:00Z","timestamp":1560470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Recently, there have been reports of endoscopic ultrasound\u2010guided fine\u2010needle aspiration (EUS\u2010FNA) cytology being used for the diagnosis of various kinds of tumors. This method has also been adopted in the diagnosis of gastric submucosal tumors (SMTs). The aim of this study was to analyze the utility of EUS\u2010FNA cytological examination in rapid on\u2010site evaluation (ROSE) for gastric SMTs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analyses of the cytological specimens of EUS\u2010FNA in ROSE for gastric SMTs and determination of the diagnostic accuracy of EUS\u2010FNA combined with immunohistochemical analysis of cell blocks and surgically resected specimens were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 110 patients were enrolled in this study. The most common cytodiagnosis was spindle cell tumor (62 patients, 55.5%), followed by negative for tumor (34 patients), and malignant lymphoma and adenocarcinoma (five patients each). Cell blocks were prepared for 60 of the patients (96.8%), cytologically diagnosed with spindle cell tumor. Immunohistochemical analyses using cell block revealed gastrointestinal stromal tumor (GIST, c\u2010kit<jats:sup>+<\/jats:sup>\/desmin<jats:sup>\u2212<\/jats:sup>, 49 patients) and leiomyoma (desmin<jats:sup>+<\/jats:sup>\/c\u2010kit<jats:sup>\u2212<\/jats:sup>, five patients). Thus, using EUS\u2010FNA specimens, 83.1% of GIST patients were pre\u2010operatively diagnosed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>EUS\u2010FNA cytological examination in ROSE for gastric SMTs aided in the collection of sufficient amounts of tumor tissues for preparing cell blocks. This method led to a high rate of accurate pre\u2010operative diagnosis in patients with gastric SMTs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24252","type":"journal-article","created":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T14:50:05Z","timestamp":1560523805000},"page":"869-875","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Utility of endoscopic ultrasound\u2010guided fine\u2010needle aspiration cytology in rapid on\u2010site evaluation for the diagnosis of gastric submucosal tumors: Retrospective analysis of a single\u2010center experience"],"prefix":"10.1002","volume":"47","author":[{"given":"Kaori","family":"Sandoh","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0607-8920","authenticated-orcid":false,"given":"Mitsuaki","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimiaki","family":"Okano","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chika","family":"Miyasaka","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeo","family":"Mori","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Kansai Medical University  Osaka Japan"},{"name":"Mori Internal Medicine and Dermatology Clinic  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuo","family":"Tokuhara","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryou","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohiro","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Tsuta","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Kansai Medical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24121"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23870"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12149"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.11.044"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23976"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12157"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10003"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1309\/NL2WYAD8EUH3XFRF"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2002.120323"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1214447"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.15403\/jgld.2014.1121.234.eug"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.22913"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.59.7344"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1309\/M1EC8JE9ACAMJACU"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.24252","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24252","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24252","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T15:59:56Z","timestamp":1694275196000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,14]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1002\/dc.24252"],"URL":"https:\/\/doi.org\/10.1002\/dc.24252","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,14]]},"assertion":[{"value":"2019-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}