{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T22:28:11Z","timestamp":1749421691568,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T00:00:00Z","timestamp":1560729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>India, being a developing country, harbors the third largest human immunodeficiency virus (HIV)\u2010infected population in the world, and HIV\u2010associated lymphadenopathy is commonly encountered. HIV lymphadenopathy is more commonly generalized and pathology ranges from reactive lymphoid hyperplasia to infections like tuberculosis to neoplasms such as lymphoma and Kaposi sarcoma. The study intended to assess the utility of fine\u2010needle aspiration (FNA) cytology in HIV lymphadenopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A retrospective FNA slide review of HIV\u2010infected cases with lymphadenopathy received over a period of 2 years in the cytopathology department was performed. The clinicopathological characteristics, absolute lymphocyte count (ALC), and CD4 counts were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010nine lymph node aspirates were received from HIV patients over 2 years. The mean age at presentation was 39\u2009years with a male:female ratio of 2.4:1. Cervical lymph nodes (62%) were more commonly affected. Tuberculous lymphadenitis was the commonest lesion (41.8%), followed by reactive lymphadenitis (24%), nonspecific granulomatous lymphadenitis (14%), suppurative lymphadenitis (8%), cryptococcal lymphadenitis (2%), lymphoma (9%), and metastasis (1%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Lymph node FNA in HIV\/AIDS is not only useful in identifying those cases that require further evaluation, but also aids in categorizing various etiologies such as opportunistic infections, non\u2010neoplastic, and neoplastic lesions. FNA is a less expensive, expeditious minimally invasive method for an early diagnosis that abets in deciding the treatment strategy, thus curtailing the associated morbidity and mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24255","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T17:24:19Z","timestamp":1560792259000},"page":"1011-1017","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Utility of fine\u2010needle aspiration cytology in the diagnosis of HIV lymphadenopathy"],"prefix":"10.1002","volume":"47","author":[{"given":"Pooja K.","family":"Suresh","sequence":"first","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Mangalore Manipal Academy of Higher Education  Manipal Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shweta","family":"Poojary","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Mangalore Manipal Academy of Higher Education  Manipal Karnataka India"},{"name":"Department of Radiodiagnosis Junior Resident, Bangalore Medical College and Research Centre  Bangalore Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5325-7086","authenticated-orcid":false,"given":"Sridevi Hanganahalli","family":"Basavaiah","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Mangalore Manipal Academy of Higher Education  Manipal Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyoti R.","family":"Kini","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Mangalore Manipal Academy of Higher Education  Manipal Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flora D.","family":"Lobo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Mangalore Manipal Academy of Higher Education  Manipal Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kausalya K.","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kasturba Medical College, Mangalore Manipal Academy of Higher Education  Manipal Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,17]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"Department of AIDS Control.Ministry of Health and Family Welfare. Annual Report; 2011\u201312."},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840080109"},{"key":"e_1_2_8_4_1","first-page":"111","article-title":"Acid\u2010fast staining patterns and their correlation with HIV positivity (Lett)","volume":"49","author":"Kumar S","year":"2005","journal-title":"Acta Cytol"},{"key":"e_1_2_8_5_1","first-page":"546","article-title":"Use of fine needle aspiration cytology for investigating lymphadenopathy in HIV positive patients","volume":"46","author":"Bates EM","year":"1993","journal-title":"J Clin Pathol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2303.1998.00149.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000326713"},{"key":"e_1_2_8_8_1","first-page":"4","article-title":"FNA of peripheral lymphadenopathy in HIV positive patients","volume":"1","author":"Kumar guru BN","year":"2009","journal-title":"Sci Med"},{"key":"e_1_2_8_9_1","first-page":"37","article-title":"Diagnostic utility of FNA in HIV positive lymphadenopathy","volume":"3","author":"Parikh UR","year":"2012","journal-title":"J Clin Res Lett"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2009.00712.x"},{"key":"e_1_2_8_11_1","first-page":"301","article-title":"Lymph nodes cytology in HIV\u20101 seropositive cases with haematological alterations","volume":"139","author":"Tirumalasetti N","year":"2014","journal-title":"Indian J Med Res"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijtb.2016.08.008"},{"key":"e_1_2_8_13_1","first-page":"150","article-title":"Diagnostic challenges in cervical tuberculous lymphadenitis: a review","volume":"3","author":"Deveci HS","year":"2016","journal-title":"North Clin Istanbul"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/2141-9248.133466"},{"key":"e_1_2_8_15_1","first-page":"95","volume-title":"Ioachim's Lymph Node Pathology","author":"Ioachim HL","year":"2002"},{"key":"e_1_2_8_16_1","first-page":"12","article-title":"Review of HIV\u2010related cytopathology","volume":"2011","author":"Lang Tee U.","year":"2011","journal-title":"Patholog Res Int"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.24255","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24255","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24255","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T03:46:46Z","timestamp":1694317606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,17]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/dc.24255"],"URL":"https:\/\/doi.org\/10.1002\/dc.24255","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2019,6,17]]},"assertion":[{"value":"2019-02-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}