{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:38:12Z","timestamp":1788917892115,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Primary salivary gland\u2010type tumors of the tracheobronchial tree are rare; their cytologic features have been seldom reported. We aim to describe the clinical and cytomorphologic features of tracheobronchial salivary gland\u2010type tumors diagnosed by transbronchial fine needle aspiration (TBNA) at our institution, and correlate the findings with a corresponding surgical specimen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched our laboratory information system to identify patients with a primary salivary gland\u2010type neoplasm of the tracheobronchial tree diagnosed by TBNA and with a corresponding surgical pathology specimen, over 10 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study cohort consisted of 11 patients (7F\/4M; mean age 58\u2009years, range 41\u201078). Presenting symptoms included hemoptysis (4), cough (3), dyspnea (1), stridor (1), and shoulder pain (1). Most had a tracheal mass (5), while 3 had mainstem bronchi masses and 3 had lung masses. Radiographically, the masses were lobulated, rounded, or polypoid in six patients. All underwent TBNA with a 21\u2010 or 22\u2010gauge needle and endobronchial biopsy. The most frequent diagnosis was adenoid cystic carcinoma (4\/11, 36%), followed by mucoepidermoid carcinoma (3\/11, 27%), epithelial\u2010myoepithelial carcinoma (2\/11, 18%), oncocytoma (1\/11, 9%), and hyalinizing clear cell carcinoma, salivary gland type (1\/11, 9%). The surgical pathology specimens confirmed the diagnosis in all cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To our knowledge, this is one of the largest cytomorphologic studies of primary salivary gland tumors of the tracheobronchial tree in the literature. Salivary gland tumors of the tracheobronchial tree are rare, and recognizing cytomorphologic changes that occur in salivary gland\u2010type tumors is important for establishing a definitive diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24285","type":"journal-article","created":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T13:01:13Z","timestamp":1564059673000},"page":"1168-1176","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Primary salivary gland\u2010type tumors of the tracheobronchial tree diagnosed by transbronchial fine needle aspiration: Clinical and cytomorphologic features with histopathologic correlation"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6425-6537","authenticated-orcid":false,"given":"Erika E.","family":"Doxtader","sequence":"first","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akeesha A.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaxia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital for Special Surgery  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Robert Wood Johnson Medical School Rutgers University  New Brunswick New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn S.","family":"Dyhdalo","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Farver","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000099"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23048"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23423"},{"key":"e_1_2_8_5_1","first-page":"106","article-title":"Primary salivary gland\u2010type tumors of the lung","volume":"12","author":"Moran CA","year":"1995","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3182a7d272"},{"key":"e_1_2_8_7_1","first-page":"267","article-title":"An uncommon primary lung tumor: hyalinizing clear cell carcinoma, salivary gland\u2010type","volume":"67","author":"Shah AA","year":"2014","journal-title":"Histopathol"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-017-0820-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2014.11.010"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqx048"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0339(200011)23:5<333::AID-DC10>3.0.CO;2-R"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21733"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2017.00043"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21431"},{"issue":"5","key":"e_1_2_8_15_1","first-page":"e211S\u2010e250S","article-title":"Methods for staging non\u2010small cell lung cancer. 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