{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T18:22:36Z","timestamp":1766514156466,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T00:00:00Z","timestamp":1573516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vaping\u2010induced lung injury is a recently recognized phenomenon owing to the rising popularity of e\u2010cigarette use. A cluster of cases of varying severity, including six deaths, was recently reported in the United States by the Centers for Disease Control. The objective of this report is to highlight the cytologic features suggestive of vaping\u2010induced lung injury. A 20\u2010year\u2010old previously healthy man presented with a 7\u2010day history of progressively worsening respiratory symptoms including dyspnea on exertion, cough, and fever, with no improvement after initiating a course of antibiotics. No relevant travel or occupational history was reported, but patient endorsed daily use of e\u2010cigarette with a fluid containing both tetrahydrocannabinol and nicotine. Radiographic studies demonstrated scattered areas of interlobular septal thickening and diffuse ground\u2010glass opacities in both lungs. Laboratory tests for HIV and influenza were negative. Bronchoscopy and bronchoalveolar lavage were performed, with cytologic study showing clusters of benign bronchial cells and an increase in lipid\u2010laden macrophages by Oil Red O stain. Patient was placed on steroid and steadily improved for the next 2\u2009days. He was discharged on a steroid taper and follow\u2010up with respiratory clinic. Case reports and series have shown a variety of lung injury patterns in previously healthy patients who are frequent users of e\u2010cigarettes and among them features suggestive of lipoid pneumonia with increased lipid\u2010laden macrophages. The clinical utility of this finding is still unclear.<\/jats:p>","DOI":"10.1002\/dc.24343","type":"journal-article","created":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T12:45:47Z","timestamp":1573562747000},"page":"174-176","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cytologic features of vaping\u2010induced lung injury: A case report"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5978-5813","authenticated-orcid":false,"given":"Fernando Alekos","family":"Ocampo\u2010Gonzalez","sequence":"first","affiliation":[{"name":"Department of Pathology Rush University Medical Center  Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u2010Weon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pathology Rush University Medical Center  Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,12]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"E\u2010cigarette use among youth and young adults: a report of the surgeon general. Rockville MD: Department of Health and Human Services.https:\/\/e\u2010cigarettes.surgeongeneral.gov\/documents\/2016_SGR_Full_Report_508.pdf2016. Accessed September 15 2019."},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6836e2"},{"key":"e_1_2_5_4_1","article-title":"Respiratory failure caused by lipoid pneumonia from vaping e\u2010cigarettes","volume":"2018","author":"Viswam D","year":"2018","journal-title":"BMJ Case Rep"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6836e1"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1912038"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1913069"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21467"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1911614"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2016.01.009"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqz182"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.24343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24343","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T06:46:05Z","timestamp":1694155565000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,12]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1002\/dc.24343"],"URL":"https:\/\/doi.org\/10.1002\/dc.24343","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2019,11,12]]},"assertion":[{"value":"2019-09-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}