{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T04:18:16Z","timestamp":1790050696138,"version":"4.0.1"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The phenotypical identification of diagnostic cells is crucial for the diagnosis of Hodgkin's lymphoma (HL) on fine\u2010needle aspiration cytology (FNAC). The aim of this study is to evaluate the immunocytochemical (ICC) expression of CD30, CD15, and PAX5 in Hodgkin's cells (HC) and Reed\u2010Sternberg cells (RSC) on smears and cell\u2010blocks (CB) of HL and to compare the performance of each antibody on smears and CB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 21 FNAC cases of histologically confirmed classical HL, ICC identification of HC and RSC was performed using CD15, CD30, and PAX5 on smears and CB, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CD30 was positive in 19\/21 cases (90.5%; 11\/11 smears and 8\/10 CB), CD15 was positive in 14\/21 cases (66.7%; 5\/11 smears and 9\/10 CB), and PAX5 was positive in 13\/21 cases (61.9%; 9\/11 smears and 4\/10CB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CD15, CD30, and PAX5 are useful to the FNAC identification of HC and RSC. CD30 is the most sensitive, followed by CD15 and PAX5, which are more effective on CB and smears, respectively.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24366","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T12:36:20Z","timestamp":1576067780000},"page":"211-216","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["CD15, CD30, and PAX5 evaluation in Hodgkin's lymphoma on fine\u2010needle aspiration cytology samples"],"prefix":"10.1002","volume":"48","author":[{"given":"Immacolata","family":"Cozzolino","sequence":"first","affiliation":[{"name":"Department of Physical and Mental Health and Preventive Medicine School of Medicine and Surgery Universit\u00e0 degli Studi della Campania \u201cLuigi Vanvitelli\"  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Vitagliano","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Salerno, University of Napoli \u201cFederico II\u201d  Fisciano SA Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5139-3869","authenticated-orcid":false,"given":"Alessandro","family":"Caputo","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery University of Salerno  Fisciano SA Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Montella","sequence":"additional","affiliation":[{"name":"Department of Physical and Mental Health and Preventive Medicine School of Medicine and Surgery Universit\u00e0 degli Studi della Campania \u201cLuigi Vanvitelli\"  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8340-3184","authenticated-orcid":false,"given":"Renato","family":"Franco","sequence":"additional","affiliation":[{"name":"Department of Physical and Mental Health and Preventive Medicine 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