{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:28:30Z","timestamp":1765232910668,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T00:00:00Z","timestamp":1591488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Carcinoma of the gall bladder is the most common malignancy of the biliary tract. Ultrasonography guided Fine Needle Aspiration Cytology (FNAC) plays a crucial role in early detection of gall bladder (GB) lesions. Early diagnosis of GB lesions is a necessity in view of rising trend in GB carcinoma related mortality in India. The aim of this study is to determine the diagnostic accuracy of pre\u2010operative ultrasonography guided FNAC in the diagnosis of GB masses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective observational study performed at a tertiary care university hospital over a period of one and a half years. A total of 47 patients with clinico\u2010radiological suspicion of GB malignancy were subjected to USG guided FNA. 20 of these patients underwent diagnostic Trucut biopsy in addition to FNA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one out of 47 patients analyzed were positive for malignancy with female preponderance; MF ratio of 0.6:1. There were 29 females (61.8%) and 18 males (38.2%) in the range of 34 to 85\u2009years. Cytomorphology was inconclusive for malignancy in two patients and unsatisfactory in one case. Two were labeled as chronic cholecystitis and one as acute cholecystitis. Adenocarcinoma was the most common malignancy found in 36 patients (76.6%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>USG guided FNAC is a rapid, safe and successful diagnostic procedure with high sensitivity for diagnosis of GB lesions. In the present scenario of increasing incidence of GB malignancy, FNAC has proved to be a useful first choice of investigation in the detection of GB lesions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24517","type":"journal-article","created":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T14:22:31Z","timestamp":1591539751000},"page":"1081-1085","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic role of fine needle aspiration cytology (<scp>FNAC<\/scp>) in the evaluation of gall bladder lesions: an institutional experience"],"prefix":"10.1002","volume":"48","author":[{"given":"Pavneet Kaur","family":"Selhi","sequence":"first","affiliation":[{"name":"Department of Pathology Dayanand Medical College and Hospital  Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2662-1289","authenticated-orcid":false,"given":"Yasmeen","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology Dayanand Medical College and Hospital  Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pathology Dayanand Medical College and Hospital  Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Pathology Dayanand Medical College and Hospital  Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neena","family":"Sood","sequence":"additional","affiliation":[{"name":"Department of Pathology Dayanand Medical College and Hospital  Ludhiana Punjab India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3126\/jpn.v1i1.4444"},{"key":"e_1_2_8_3_1","first-page":"24","article-title":"Epidemiology of digestive tract cancers in India IV","volume":"18","author":"Dhir V","year":"1999","journal-title":"Gallbladder and Pancreas Indian J Gastroenterol"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.51.6.349"},{"volume-title":"Consolidated Reports of the Population Based Cancer Registries 1990\u20131996","year":"2001","author":"National Cancer Registry Programme","key":"e_1_2_8_5_1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199804)18:4<258::AID-DC2>3.0.CO;2-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(03)01021-0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198203000-00005"},{"key":"e_1_2_8_9_1","first-page":"170","article-title":"Management of carcinoma of the gallbladder","volume":"3","author":"Nagorney DM","year":"1986","journal-title":"Probl Gen Surg"},{"key":"e_1_2_8_10_1","first-page":"106","article-title":"Carcinoma of the gallbladder and extrahepatic bile ducts","volume":"15","author":"Nagorney DM","year":"1988","journal-title":"Semin Oncol"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19921001)70:7<1838::AID-CNCR2820700705>3.0.CO;2-G"},{"volume-title":"Tumors of the Gallbladder and Extrahepatic Bile Ducts: Atlas of Tumor Pathology. 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