{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T12:22:45Z","timestamp":1786191765991,"version":"build-2736575974"},"reference-count":46,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T00:00:00Z","timestamp":1594166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The Milan system for Reporting Salivary Gland Cytopathology (MSRSGC) was published in 2018. Since then, many authors have published their institutional experience by retrospectively assigning salivary gland fine\u2010needle aspiration cases to each of the MSRSGC categories and calculated their risk of malignancy (ROM) accordingly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed all published articles available online in English that used the MSRSGC since or near its publication. We calculated the risk of neoplasm and ROM for each diagnostic category. In addition, the false\u2010negative and false\u2010positive rates from all studies were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010seven articles were identified in the English literature; 2 were published in 2017, 14 in 2018, 18 in 2019, and 3 in 2020. The total number of cases was 16\u2009394, and 8\u2009468 had surgical follow\u2010up. The mean ROM was 16.9% for category I, 10.5% for category II, 39.3% for category III, 2.9% for category IVa, 39.4% for category IVb, 84.2% for category V, and 97.5% for category VI. The mean false\u2010negative rate for MSRSGC categories II and IVa was 4.5%. Similarly, the mean false\u2010positive rate for MSRSGC categories V and VI was 5.1%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A tiered classification scheme of MSRSGC is helpful in effectively guiding clinical management of patients with salivary gland lesions. The reported mean ROM for each category in most studies is within the recommended range published by the MSRSGC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24536","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T18:14:30Z","timestamp":1594232070000},"page":"880-889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["The Milan system for reporting salivary gland cytopathology: A comprehensive review of the literature"],"prefix":"10.1002","volume":"48","author":[{"given":"Jalal B.","family":"Jalaly","sequence":"first","affiliation":[{"name":"Department of Pathology Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar J.","family":"Farahani","sequence":"additional","affiliation":[{"name":"Department of Pathology Renaissance School of Medicine, Stony Brook University, University Hospital  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9342-3069","authenticated-orcid":false,"given":"Zubair W.","family":"Baloch","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-71285-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24097"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000224"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488969"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22040"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24347"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/JOC.JOC_191_18"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24269"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24279"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22150"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25804"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11121912"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24196"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22208"},{"issue":"1","key":"e_1_2_7_16_1","article-title":"Risk assessment of salivary gland cytological categories of the Milan system: a retrospective cytomorphological and immunocytochemical institutional study","volume":"1","author":"HAFEZ, NH","year":"2019","journal-title":"Turk J Pathol"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22066"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21989"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.30699\/ijp.13.2.220"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/JOC.JOC_165_18"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24321"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12562"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22245"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.4103\/cytojournal.cytojournal_45_18"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22002"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24350"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22135"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2019.04.001"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.4103\/IJPM.IJPM_662_17"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24037"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.4103\/JOC.JOC_68_18"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12811"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12816"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24109"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21900"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24214"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24063"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12642"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12557"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11101589"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1159\/000492051"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22016"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23826"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqz006"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.19163"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24187"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2019.12.002"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.24536","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24536","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24536","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T13:00:23Z","timestamp":1693918823000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,8]]},"references-count":46,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1002\/dc.24536"],"URL":"https:\/\/doi.org\/10.1002\/dc.24536","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,8]]},"assertion":[{"value":"2020-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}