{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:52:14Z","timestamp":1747147934275,"version":"3.40.5"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T00:00:00Z","timestamp":1594598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Desmoplastic small round cell tumor (DSRCT) is rare and a highly aggressive neoplasm that typically involves the soft tissues of the abdomen or pelvis in children or young adults, showing a male predilection. Although it can occurs over a wide age range, the peak incidence is in the third decade of life. DSRCT usually shows widespread abdominal serosal involvement, and overall patient survival is poor. On the other hand, extra\u2010abdominal DSRCT is very rare. DSRCT in major salivary glands has been reported, but it is extremely rare. In the majority of reported series diagnosis is made by the histological analysis of FFPE tissues together with immunohistochemistry (IHC) and molecular analysis, particularly the demonstration of chromosomal translocation involving EWSR1. Very few cases have been diagnosed so far by Fine Needle Aspiration (FNA) cytology. Moreover ancillary studies have been performed in all reported cases in FFPE samples. There is still controversy and lack of consensus regarding the suitability of cytological samples especially smears for immunocytochemical (ICC) and fluorescence in situ hybridization (FISH), what makes its standardization difficult. We report a case of a primary DSRCT of parotid gland in a 17\u2010year\u2010old male diagnosed by FNA cytology. The cytomorphological diagnosis was coupled with ICC and FISH analysis performed on stained smears. We emphasize the feasibility and reliability of cytological smears for the application of immunocytochemical and molecular techniques.<\/jats:p>","DOI":"10.1002\/dc.24542","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T12:19:22Z","timestamp":1594642762000},"page":"827-832","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A comprehensive diagnosis of a desmoplastic small round cell tumor of unusual location based on fine\u2010needle aspiration cytology: Report of a case arising in the parotid gland and review of the literature"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6796-9380","authenticated-orcid":false,"given":"Mar\u00eda D.","family":"Lozano","sequence":"first","affiliation":[{"name":"Department of Pathology Cl\u00ednica University of Navarra  Pamplona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Landa","sequence":"additional","affiliation":[{"name":"Medical Oncology University Hospital of San Sebastian  San Sebastian Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura G.","family":"Tobar","sequence":"additional","affiliation":[{"name":"Department of Pathology Cl\u00ednica University of Navarra  Pamplona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"De Andrea","sequence":"additional","affiliation":[{"name":"Department of Pathology Cl\u00ednica University of Navarra  Pamplona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Larrache","sequence":"additional","affiliation":[{"name":"Department of Radiology Cl\u00ednica University of Navarra  Pamplona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose I.","family":"Echeveste","sequence":"additional","affiliation":[{"name":"Department of Pathology Cl\u00ednica University of Navarra  Pamplona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose J.","family":"Paricio","sequence":"additional","affiliation":[{"name":"Department of Pathology Cl\u00ednica University of Navarra  Pamplona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Medical Oncology University Hospital of San Sebastian  San Sebastian Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Medina","sequence":"additional","affiliation":[{"name":"Medical Oncology University Hospital of San Sebastian  San Sebastian Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Paisan","sequence":"additional","affiliation":[{"name":"Medical Oncology University Hospital of San Sebastian  San Sebastian Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"issue":"17","key":"e_1_2_6_2_1","first-page":"97","article-title":"Desmoplastic small round cell tumor of the middle ear","volume":"0494","author":"Xu J","year":"2018","journal-title":"Med (United States)"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896918817140"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5833\/jjgs.2013.0030"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehpc.2014.11.011"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-019-0825-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2005"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-017-0638-x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAI.0b013e3181eec73c"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199911000-00012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2173-5735(09)70117-6"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10316"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20244"},{"issue":"3","key":"e_1_2_6_14_1","first-page":"514","article-title":"Cytologic features of intraabdominal desmoplastic small round cell tumor: a case report","volume":"39","author":"El\u2010Kattan I","year":"1995","journal-title":"Acta Cytol"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000327875"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21415"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333549"},{"issue":"3","key":"e_1_2_6_18_1","first-page":"373","article-title":"Intraabdominal desmoplastic small round cell tumor: report of a case diagnosed by fine needle aspiration cytology","volume":"36","author":"Setrakian S","year":"1992","journal-title":"Acta Cytol"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2017-0208-RA"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12446"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896916660198"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513818909022347"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6413-2-6"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-017-2207-y"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(99)90119-3"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2005.01.005"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MP.0000056630.76035.F3"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200003000-00010"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23829"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21784"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21215"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasc.2019.07.007"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21899"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2011.00867.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/114.3.345"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21835"},{"issue":"1","key":"e_1_2_6_37_1","first-page":"1526","article-title":"Desmoplastic small round\u2010cell tumor: Prolonged progression\u2010free survival with aggressive multimodality therapy","volume":"14","author":"Lee V","year":"2017","journal-title":"J Clin Oncol"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00518"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.24542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24542","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24542","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24542","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T20:01:41Z","timestamp":1693944101000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,13]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1002\/dc.24542"],"URL":"https:\/\/doi.org\/10.1002\/dc.24542","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2020,7,13]]},"assertion":[{"value":"2020-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}