{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:08:22Z","timestamp":1782256102282,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T00:00:00Z","timestamp":1598313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fine needle aspiration cytology (FNAC) is the first diagnostic step in patient with cervical lymphadenopathy because of its simplicity, safety and early availability of the results. Liquid\u2010based cytology (LBC) is an alternative processing method which is used for both gynecological and nongynecological samples. Literature reviewed show few studies comparing LBC with conventional preparation (CP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The present study was undertaken to evaluate the efficacy of LBC and comparison of LBC and CP in cervical lymphadenopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In this prospective study, a total of 75 cases of FNAC with cervical lymphadenopathy were included. The first pass was used for CP followed by LBC with the use of SurePath (SP) technique. Both the smears were compared for cellularity, background containing blood, cell debris, lymphoglandular bodies, stromal fragments, cytoarchitectural pattern, etc., by semiquantitative scoring system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no statistical difference in the cellularity, cell architecture, and monolayer cells (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05). On the basis of background containing blood, cell debris, lympho\u2010glandular bodies, stromal fragments (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), nuclear, and cytoplasmic details (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05), LBC was found to be superior to CP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LBC is a relatively simple technique and superior to CP in respect of better nuclear and cytoplasmic details with loss of background blood and debris. It has a diagnostic accuracy equivalent to that of CP. However, use of both LBC and CP can result in better diagnostic accuracy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24589","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T02:58:32Z","timestamp":1598410712000},"page":"18-24","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Fine needle aspiration cytology of cervical lymph nodes: Comparison of liquid based cytology (<scp>SurePath<\/scp>) and conventional preparation"],"prefix":"10.1002","volume":"49","author":[{"given":"Archana","family":"Budhwar","sequence":"first","affiliation":[{"name":"Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0440-8260","authenticated-orcid":false,"given":"Sant Prakash","family":"Kataria","sequence":"additional","affiliation":[{"name":"Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Kumar","sequence":"additional","affiliation":[{"name":"Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gajender","family":"Singh","sequence":"additional","affiliation":[{"name":"Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Kaushik","sequence":"additional","affiliation":[{"name":"Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeev","family":"Sen","sequence":"additional","affiliation":[{"name":"Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2033"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.41678"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.138669"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.155225"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23402"},{"issue":"2","key":"e_1_2_8_7_1","first-page":"245","article-title":"Liquid based preparations (LBP) cytology versus conventional cytology (CS) in FNA samples from breast, thyroid, salivary glands and soft tissues. Our experience in Crete (Greece)","volume":"50","author":"Mygdakos N","year":"2009","journal-title":"Rom J Morphol Embryol"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000363123"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000325546"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-60570-8_1"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-71285-7_1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-22864-8_10"},{"issue":"3","key":"e_1_2_8_13_1","first-page":"159","article-title":"Comparison of Thinprep and conventional smears in head and neck fine needle aspiration cytology","volume":"24","author":"Koybasioglu F","year":"2008","journal-title":"Turk J Pathol"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.190446"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000326224"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.190444"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20698"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333999"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.30699\/ijp.13.2.188"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-9294.2009.01068.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000437380"},{"key":"e_1_2_8_22_1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1159\/000362805","article-title":"Liquid based cytology in fine needle aspiration of breast lesions: a review","volume":"58","author":"Erhard R","year":"2014","journal-title":"Acta Cytol"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000351306"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24589","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24589","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24589","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T06:55:53Z","timestamp":1693810553000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24589"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,25]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/dc.24589"],"URL":"https:\/\/doi.org\/10.1002\/dc.24589","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,25]]},"assertion":[{"value":"2018-10-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}