{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:44:52Z","timestamp":1778561092353,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T00:00:00Z","timestamp":1602460800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Adenomatous neuroendocrine tumors of the middle ear (MEANTs) are very rare neoplasms which are composed of both epithelial and neuroendocrine components. They have mostly bland histology and indolent biological behavior, yet they may recur and metastasize. Here we present a case of MEANT with ipsilateral local brain, bone and nerve invasion and bilateral cervical lymphadenopathy in a 48\u2009years old male with history of recurrent chronic otitis media and cholesteatoma. The patient underwent an initial fine\u2010needle aspiration biopsy (FNAB) of an enlarged cervical lymph node followed by surgical excision of the tumor and immunohistochemistry which confirmed the diagnosis.<\/jats:p>","DOI":"10.1002\/dc.24640","type":"journal-article","created":{"date-parts":[[2020,10,12]],"date-time":"2020-10-12T18:22:17Z","timestamp":1602526937000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Adenomatous neuroendocrine tumors of the middle ear (<scp>MEANTs<\/scp>) with local invasion and lymph nodes metastasis: A brief report of a rare neoplasm"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0132-7414","authenticated-orcid":false,"given":"Linlin","family":"Yang","sequence":"first","affiliation":[{"name":"The Department of Pathology Montefiore Medical Center\/Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4568-6061","authenticated-orcid":false,"given":"Saeed","family":"Asiry","sequence":"additional","affiliation":[{"name":"The Leopold G. Koss Division of Cytopathology, Montefiore Medical Center\/Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samer N.","family":"Khader","sequence":"additional","affiliation":[{"name":"Division of Cytopathology University of Pittsburgh Medical Center (UPMC)  Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001905"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199901)21:1<72::AID-HED10>3.0.CO;2-G"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1976.tb00637.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197608000-00004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/84.4.541"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/73.6.816"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000175069.13685.37"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880561"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1626-0002-0000006508"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-017-2155-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1601400"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-018-0924-4"},{"key":"e_1_2_7_15_1","volume-title":"WHO Classification of Head and Neck Tumours","author":"El\u2010Naggar AK","year":"2017"},{"issue":"9","key":"e_1_2_7_16_1","first-page":"3453","article-title":"Neuroendocrine neoplasms of the middle ear: report of 2 cases and review of the literature","volume":"12","author":"He S","year":"2019","journal-title":"Int J Clin Exp Pathol"},{"issue":"2","key":"e_1_2_7_17_1","first-page":"121","article-title":"Neuroendocrine adenoma of the middle ear (NAME) mimicking as chronic otitis media with an episode of facial nerve palsy","volume":"7","author":"Tomazic PV","year":"2011","journal-title":"B\u2010ENT"},{"key":"e_1_2_7_18_1","first-page":"9834750","article-title":"Neuroendocrine adenoma of the middle ear: a rare histopathological diagnosis","volume":"2016","author":"Hasan Z","year":"2016","journal-title":"Case Rep Otolaryngol"},{"issue":"106","key":"e_1_2_7_19_1","first-page":"305","article-title":"Neuroendocrine adenoma of middle ear causing acute onset facial palsy\u2014a rare case report","volume":"31","author":"Zaman SU","year":"2019","journal-title":"Iran J Otorhinolaryngol"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2031"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23434"},{"issue":"5","key":"e_1_2_7_22_1","first-page":"8062","article-title":"Significance of cytodiagnosis in primary carcinoid tumor of the middle ear: a case report","volume":"15","author":"Sato K","year":"2018","journal-title":"Oncol Lett"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24640","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24640","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T10:35:19Z","timestamp":1693650919000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,12]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1002\/dc.24640"],"URL":"https:\/\/doi.org\/10.1002\/dc.24640","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,12]]},"assertion":[{"value":"2020-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}