{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:21:58Z","timestamp":1760300518467,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T00:00:00Z","timestamp":1610582400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fine\u2010needle aspiration cytology (FNAC) is an established technique for preoperative diagnosis of salivary gland lesions; however, lack of a uniform reporting system has been a handicap. The main aims of this study were to evaluate the utility of the \u2013 \u201cThe Milan System for Reporting Salivary Gland Cytopathology\u201d (MSRSGC) and ascertain the risk of malignancy (ROM) for each category.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All salivary gland FNACs over 5\u2009years (January 2014\u2010December 2018) were reviewed and assigned a diagnostic category from the MSRSGC. Clinical data were taken from Cytology records. Cytodiagnosis was correlated with histopathology wherever available and ROM was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 120 salivary gland FNACs were studied. Age ranged between 5 and 85\u2009years, male:female ratio was 2:1 and parotid was the commonest gland aspirated. Cases were reclassified as I non\u2010diagnostic (2.5%), II non\u2010neoplastic (15%), III atypia of uncertain significance\u2010AUS (1.7%), IV A neoplasm benign (50%), IV B neoplasm of uncertain malignant potential (12.5%), V suspicious for malignancy (5%), and VI malignant (13.3%). Follow\u2010up was available in 70 (58.3%) cases. The sensitivity, specificity, negative predictive value, and positive predictive value were 92.3%, 100%, 100%, and 98.27% respectively. ROM was non\u2010neoplastic (0%), AUS (50%), neoplasm benign (0%), neoplasm of uncertain malignant potential (28.6%), suspicious for malignancy (100%), and malignant (100%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Salivary gland FNAC is a reliable diagnostic tool and the \u201cMilan system\u201d will further increase FNA reliability, help risk stratification, and improve patient care.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24697","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T19:46:31Z","timestamp":1610739991000},"page":"500-508","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Utility of the Milan system for reporting salivary gland cytopathology: A retrospective 5\u2009years study"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7557-8398","authenticated-orcid":false,"given":"Jyoti","family":"Chirmade","sequence":"first","affiliation":[{"name":"Department of Pathology Seth Gordhandas Sunderdas Medical College and KEM Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanchan","family":"Kothari","sequence":"additional","affiliation":[{"name":"Department of Pathology Seth Gordhandas Sunderdas Medical College and KEM Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leena","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Pathology Lokmanya Tilak Municipal Medical College and General Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3354-2637","authenticated-orcid":false,"given":"Mona","family":"Agnihotri","sequence":"additional","affiliation":[{"name":"Department of Pathology Seth Gordhandas Sunderdas Medical College and KEM Hospital  Mumbai India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-029X.185899"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2011.01069.x"},{"issue":"7","key":"e_1_2_9_4_1","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.21276\/sjams.2016.4.7.6","article-title":"Cytohistological study of salivary gland lesions","volume":"4","author":"Devi DKR","year":"2016","journal-title":"Sch J Appl Med 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