{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:52:34Z","timestamp":1747147954748,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Fine needle aspiration (FNA) cytology has been successfully utilized in the preoperative diagnosis of oral masses. Lymphoma involving other sites has also been diagnosed frequently on FNA. Oral cavity lymphoma (OL) is rare and is clinically indistinguishable from other lesions of the mouth. A complete excision of these may be difficult. Our experience with FNA diagnosis of 11 OLs along with histopathological correlation is reported herein in a tertiary health care setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective study, clinico pathological characteristics of patients with final diagnosis of non\u2010Hodgkin's lymphoma (NHL) were reviewed over a 7 year period. Routine cytological giemsa staining was performed in all cases along with immunocytochemistry (ICC) wherever possible. The gold standard for diagnosis of NHL was based on: (1) Histopathology and immunohistochemistry and\/or (2) Flow cytometry (FC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 11 cases were diagnosed as NHL. All showed B cell immunophenotype. Two of them were diagnosed as follicular lymphoma on histopathology. Male to female ratio was 7:4 and ranged in age from 37 to 70\u2009years. The most common site was tonsillar fossa (N = 5), followed by hard palate (N = 3), soft palate (N = 2), and buccal mucosa (N = 1). Size ranged from 1 to 6 cm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Diagnosis of OLs may be hampered by its rarity and difficulties in obtaining sufficient cellularity in oral FNA but there is need for immediate and accurate diagnostic procedures, including immunohistochemical analysis to avoid delay in treatment. FNA along with ICC helps in early diagnosis of this rare entity and can also provide sample for FC.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24700","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T20:45:07Z","timestamp":1611607507000},"page":"487-493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Utility of fine needle aspiration cytology to diagnose intraoral lymphoma: 7\u2009years study from a tertiary care center"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2047-6674","authenticated-orcid":false,"given":"Radhika","family":"Agarwal","sequence":"first","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meeta","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepika","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pritika","family":"Khushwaha","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Meher","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nita","family":"Khurana","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyama","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarika","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidhi","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Pathology and ENT Maulana Azad Medical College and Lok Nayak Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.116062"},{"key":"e_1_2_9_3_1","first-page":"245","article-title":"Systematic review of lymphoma in oral cavity and maxillofacial region","volume":"24","author":"Guevara\u2010Canales JO","year":"2011","journal-title":"Acta Odontol Latinoam"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(05)80336-1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2002.30721"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.02.019"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896907313755"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.06.002"},{"key":"e_1_2_9_9_1","first-page":"333","article-title":"Fine needle aspiration cytology of oral and pharyngeal lesions","volume":"37","author":"Das DK","year":"1993","journal-title":"A Study of 45 Cases Acta Cytol"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199908000-00009"},{"key":"e_1_2_9_11_1","first-page":"683","article-title":"Intraoral and transoral fine needle aspiration. 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