{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T07:55:25Z","timestamp":1772524525921,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstrac<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Rapid on\u2010site evaluation (ROSE) has the potential to increase endobronchial ultrasound (EBUS) guide transbronchial lung biopsy (TBLB) accuracy in the diagnosis of peripheral pulmonary lesions (PPLs). However, studies have reported controversial results. The aim of the study was to evaluate the diagnostic value of EBUS\u2010TBLB combination with ROSE in PPLs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 152 patients with PPLs underwent EBUS were enrolled and completed this study. Patients were divided into EBUS combined with ROSE group (EBUS+ROSE group) and EBUS group (EBUS group). The diagnostic yield, operation time, and complications were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The diagnostic yield in EBUS+ROSE group was 85.9%, the operation time was (24.6\u2009\u00b1\u20096.8) min, the diagnostic yield in EBUS group was 70.3%, and the operative time was (32.4\u2009\u00b1\u20098.7) min, there were significant differences in diagnostic yield (\u03c7<jats:sup>2<\/jats:sup> = 5.456, <jats:italic>P<\/jats:italic> = .016) and operation time (t = 3.167, <jats:italic>P<\/jats:italic> = .001) between the two groups. No severe procedure related complications were observed, such as, pneumothorax and hemorrhage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ROSE can improve the diagnostic yield and shorten the operation time. EBUS combined with ROSE is an effective diagnostic method for PPLs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.24725","type":"journal-article","created":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T12:47:59Z","timestamp":1614257279000},"page":"706-710","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Diagnostic value of endobronchial ultrasound combined with rapid <scp>on\u2010site<\/scp> evaluation of transbronchial lung biopsy for peripheral pulmonary lesions"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8728-2183","authenticated-orcid":false,"given":"Chunhua","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Nanjing Chest Hospital  Nanjing China"},{"name":"Affiliated Nanjing Brain Hospital Nanjing Medical University  Nanjing China"},{"name":"Respiratory Medicine Clinical Center of Nanjing Respiratory Diseases and Imaging  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Nanjing Chest Hospital  Nanjing China"},{"name":"Affiliated Nanjing Brain Hospital Nanjing Medical University  Nanjing China"},{"name":"Respiratory Medicine Clinical Center of Nanjing Respiratory Diseases and Imaging  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Nanjing Chest Hospital  Nanjing China"},{"name":"Affiliated Nanjing Brain Hospital Nanjing Medical University  Nanjing China"},{"name":"Respiratory Medicine Clinical Center of Nanjing Respiratory Diseases and Imaging  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Nanjing Chest Hospital  Nanjing China"},{"name":"Affiliated Nanjing Brain Hospital Nanjing Medical University  Nanjing China"},{"name":"Respiratory Medicine Clinical Center of Nanjing Respiratory Diseases and Imaging  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huidi","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pathology Nanjing Chest Hospital  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiwang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine the First Affiliated Hospital of Nanjing Medical University  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,25]]},"reference":[{"issue":"5","key":"e_1_2_9_2_1","first-page":"142","article-title":"Diagnosis and management of lung cancer, 3rded: American college of chest physicians evidence\u2010based clinical practice 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