{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:53:06Z","timestamp":1747147986170,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:00:00Z","timestamp":1640304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This report presents the clinical and pathologic findings of three cases of metastatic amelanotic melanoma to the parotid gland. Two of the patients had a primary cutaneous tumor. Fine\u2010needle aspiration of the parotid showed clusters of epithelioid cells and\/or spindle\u2010shaped cells with vesicular nuclei, macronucleoli, and abundant eosinophilic cytoplasm. In addition, one had striking balloon\u2010cell features. In the immunohistochemical study, the tumors expressed S\u2010100, HMB\u201045 antigen, Melan\u2010A, and SOX10, and focally smooth\u2010muscle actin, cytokeratin, CD56, p63, and synaptophysin. The diagnosis was challenging because the tumors were clinically thought to be primary parotid lesion and showed unusual immunohistochemical labeling for SMA, cytokeratins, p63, and neuroendocrine markers. Furthermore, the long clinical history in two of the cases made the diagnosis of a metastatic lesion less likely. Diagnostic errors can be reduced by integrating cytomorphologic, histologic, immunohistochemical, and clinical findings.<\/jats:p>","DOI":"10.1002\/dc.24920","type":"journal-article","created":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T14:25:05Z","timestamp":1640355905000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Fine\u2010needle aspiration cytological findings in three cases of metastatic amelanotic melanoma to the parotid gland with divergent differentiation"],"prefix":"10.1002","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6638-513X","authenticated-orcid":false,"given":"Juan B.","family":"Laforga","sequence":"first","affiliation":[{"name":"Pathology Laboratory Hospital de Denia  Denia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,24]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1067\/mjd.2000.103981"},{"doi-asserted-by":"publisher","key":"e_1_2_7_3_1","DOI":"10.1001\/jamadermatol.2014.1348"},{"doi-asserted-by":"publisher","key":"e_1_2_7_4_1","DOI":"10.1002\/cncy.21798"},{"doi-asserted-by":"publisher","key":"e_1_2_7_5_1","DOI":"10.1016\/0002-9610(91)90140-9"},{"doi-asserted-by":"publisher","key":"e_1_2_7_6_1","DOI":"10.1016\/S0344-0338(86)80044-9"},{"key":"e_1_2_7_7_1","first-page":"403","volume-title":"Tumors of the Salivary Glands","author":"Ellis GL","year":"1996"},{"doi-asserted-by":"publisher","key":"e_1_2_7_8_1","DOI":"10.1002\/dc.21010"},{"doi-asserted-by":"publisher","key":"e_1_2_7_9_1","DOI":"10.1016\/j.critrevonc.2010.04.007"},{"doi-asserted-by":"publisher","key":"e_1_2_7_10_1","DOI":"10.1200\/JCO.2008.18.9845"},{"doi-asserted-by":"publisher","key":"e_1_2_7_11_1","DOI":"10.1002\/(SICI)1097-0339(200002)22:2<97::AID-DC7>3.0.CO;2-V"},{"doi-asserted-by":"publisher","key":"e_1_2_7_12_1","DOI":"10.1002\/jso.25317"},{"doi-asserted-by":"publisher","key":"e_1_2_7_13_1","DOI":"10.1001\/archoto.2010.104"},{"doi-asserted-by":"publisher","key":"e_1_2_7_14_1","DOI":"10.1159\/000325253"},{"doi-asserted-by":"publisher","key":"e_1_2_7_15_1","DOI":"10.1002\/dc.10253"},{"doi-asserted-by":"publisher","key":"e_1_2_7_16_1","DOI":"10.1097\/01.pas.0000213314.74423.d8"},{"doi-asserted-by":"publisher","key":"e_1_2_7_17_1","DOI":"10.1002\/dc.2840110413"},{"doi-asserted-by":"publisher","key":"e_1_2_7_18_1","DOI":"10.1136\/jclinpath-2020-206962"},{"doi-asserted-by":"publisher","key":"e_1_2_7_19_1","DOI":"10.1038\/modpathol.2013.54"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.24920","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.24920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T20:13:20Z","timestamp":1692994400000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.24920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,24]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1002\/dc.24920"],"URL":"https:\/\/doi.org\/10.1002\/dc.24920","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2021,12,24]]},"assertion":[{"value":"2021-08-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}